Biochemical variation and association of Maternal Lipid Profile with Body Mass Index during Pregnancy

The alteration of lipid profiles of healthy gestating women occurs with multiple physiological changes which may have subsequent risk associated with adverse pregnancy outcomes affecting both maternal and fetal health. Therefore, the objective of this study was focused to examine serum lipid profile and its correlation with body mass between BMI with HDL-C was negatively correlated and found to be significant (r= -0.114; p<0.01). Conclusion: The BMI and serum concentrations of TC, TG, LDL-C and VLDL-C were found to be increased in pregnant women except for HDL-C with advancement of gestational trimesters. But, serum TG and VLDL-C was decreased in 1 st trimester of pregnancy as compared with non-pregnant healthy women. The relationship between BMI and lipid profile was positively correlated and highly significant for all the blood lipid profile except for HDL-C. However, there was negative correlation between BMI and HDL-C and was found to be significant. Gynecologists should recommend blood lipid profile to be integrated as routine investigation during antenatal care visits to avoid future complications in both mother and fetus.