一名孕妇死于心源性猝死:食道异物是否应被视为诱发因素?病例报告及文献综述

Chang Cao, Mingming Li, Zhan-xiang Liu, S. Fang, Gang Chen, Guang-ping Chen, Tongjun Ma, Xuyang Zhu, Xiang Xu
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引用次数: 0

摘要

在此,我们报告一例冠心病急性发作病例。一名患有妊娠期高血压的47岁孕妇入院后突然出现胸闷、心悸、呼吸困难和面部和嘴唇发绀。当时她的血压为180/110毫米汞柱,血氧饱和度为45%。心肺复苏后,微弱的心跳恢复了,但血氧饱和度没有显著增加。因此,她被转移到重症监护室;然而,她在入院21天后去世。尸检结果显示,右侧梨状肌附近的食道内埋有异物,她的心脏重392克;组织病理学检查显示CHD、右冠状动脉管腔血栓形成、心肌细胞肥大、小动脉血管透明变性、细支气管和肺泡中性粒细胞。所有测试样品的毒理学结果均为阴性。临床状况和尸检结果与围产期心肌病的诊断不一致。患者的猝死归因于CHD,食管异物嵌塞被认为是伴随现象。我们的研究结果可能有助于提高人们对食管异物嵌塞和心脏性猝死的认识,也有助于澄清了解死亡的主要原因是解决医源性医疗纠纷的关键。
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A pregnant woman died of sudden cardiac death: Should esophageal foreign body be considered an inductive factor? A case report and literature review
Here, we report a case of acute attack of coronary heart disease (CHD). A 47-year-old pregnant woman with gestational hypertension developed sudden-onset chest tightness, palpitations, dyspnea, and cyanosis of the face and lips after admission. Her blood pressure was 180/110 mmHg and her blood oxygen saturation was 45% at that time. After cardiopulmonary resuscitation, a weak heartbeat was restored, but oxygen saturation did not increase significantly. Therefore, she was transferred to the intensive care unit; however, she died after 21 days of admission. Autopsy findings revealed that a foreign body was embedded in the esophagus near the right piriform, and her heart weighed 392 g; histopathological examination revealed CHD, thrombosis in the lumen of the right coronary artery, cardiomyocyte hypertrophy, vascular hyaline degeneration in arterioles, neutrophils in the bronchiole and alveolar. All the tested samples yielded negative toxicological results. Clinical status and autopsy findings were not compatible with a diagnosis of peripartum cardiomyopathy. The patient's sudden death was attributed to CHD, and esophageal foreign-body impaction was considered to be concomitant phenomenon. Our findings might help in increasing the awareness between esophageal foreign-body impaction and sudden cardiac death and they can also help in clarifying that understanding the primary cause of death is the key to resolving an iatrogenic medical tangle.
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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
6
审稿时长
39 weeks
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