心脏代谢综合征:一个新出现的全球健康问题

Md. Ismail Patwary, K. Talha, Moona Farzana Razzaque, Ferdousi Jannat Liza, A. Istiaque
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摘要

心脏代谢综合征(CMS)是以胰岛素抵抗、糖耐量受损、血脂异常、高血压和中心性肥胖为特征的代谢功能障碍的综合征。CMS被世界卫生组织(世界卫生组织)和美国内分泌学学会认定为疾病实体。CMS代表了一系列代谢异常,这些代谢异常是心血管疾病的风险因素。这些心血管和代谢紊乱单独且相互依赖地导致脑血管疾病(CVD)发病率和死亡率的增加,使CMS成为早发CVD的一个既定且强大的风险因素。根据最新的国家健康和营养检查调查(NHANES),数据发现,心脏代谢综合征(CMS)在所有年龄组中的患病率都在增加,包括男性和女性。脂肪酸代谢的改变,如血浆中脂肪酸释放过多,可能会导致这些代谢异常。通过包括适度体育活动、减轻体重、严格控制血压、纠正血脂异常和控制血糖在内的治疗策略,在逆转异常反应和降低心血管风险方面有着既定且已被证明的益处。J Bangladesh Coll Phys Surg 2022;40:287-291
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Cardiometabolic Syndrome : An Emerging Global Health Issue
Cardio metabolic syndrome (CMS) is a combination of metabolic dysfunctions characterized by insulin resistance, impaired glucose tolerance, dyslipidemia, hypertension and central obesity. CMS is recognized as a disease entity by the World Health Organization (WHO) and American Society of Endocrinology. CMS represents a constellation of metabolic abnormalities that are risk factors for cardiovascular diseases These cardiovascular and metabolic derangements individually and interdependently lead to increases in cerebrovascular disease(CVD) morbidity and mortality, making the CMS an established and strong risk factor for premature CVD. Data found that the prevalence of cardiometabolic syndrome (CMS) is increasing in all age groups, both in men and women from the latest National Health and Nutritional Examination Survey (NHANES).Alteration in fatty acid metabolism, such as excessive fatty acid release in the plasma is likely to contribute to these metabolic abnormalities. There is an established and proven benefits in reversing abnormal responses and decreasing cardiovascular risks by the treatment strategies including moderate physical activity, weight reduction, rigorous blood pressure control, correction of dyslipidemia and glycaemic control. J Bangladesh Coll Phys Surg 2022; 40: 287-291
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