人畜炭疽病的传播与最优控制模型

IF 1.3 4区 数学 Q3 BIOLOGY Journal of Biological Systems Pub Date : 2022-07-30 DOI:10.1142/s0218339022500218
A. Zewdie, S. Gakkhar, Shivmurti K Gupta
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引用次数: 0

摘要

炭疽病是由炭疽杆菌引起的一种疾病,通常影响动物和人类的健康。本文提出并分析了一个包含人和动物的非线性确定性炭疽模型。对繁殖数[公式:见正文]和平衡点进行了探索,以研究疾病的动态行为。讨论了平衡点的存在性和稳定性。对于[公式:见正文],无病平衡[公式:看正文]是全局稳定的。然而,当[公式:见正文]和局部稳定的地方病平衡点[公式:看正文]存在时,它是不稳定的。然后将该模型推广到考虑人类接种、动物接种和适当胴体去除的最优控制模型。人类和动物群体的疫苗接种类别分别出现在模型中。讨论了最优控制的存在性及其特征。对参数值和初始条件的选择进行了数值模拟。这些说明了疑似地区的拾荒者以受感染的动物尸体为食,有助于减少疾病的传播。此外,还对四种不同控制策略进行了数值比较分析。我们的研究结果表明,每种控制技术对减少人类和动物种群的感染总数都有自己的影响。所有控制措施的累积影响被发现在降低疾病流行率方面非常有效。
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MODEL FOR TRANSMISSION AND OPTIMAL CONTROL OF ANTHRAX INVOLVING HUMAN AND ANIMAL POPULATION
Anthrax is a disease caused by Bacillus anthracis, commonly affects animals as well as humans health. In this paper, a nonlinear deterministic anthrax model involving human and animal is proposed and analyzed. The reproduction number [Formula: see text] and equilibrium points are explored to study the dynamic behavior of the disease. The existence and stability of equilibrium points are discussed. For [Formula: see text], the disease-free equilibrium [Formula: see text] is globally stable. However, it is unstable when [Formula: see text] and a locally stable endemic equilibrium point [Formula: see text] exists. The model is then extended to optimal control model considering human vaccination, animal vaccination and proper removal of carcass. The vaccination class of human and animal population appears separately in a model. The existence and characterization of optimal control are discussed. The numerical simulations are carried out for the choice of parametric values and initial conditions. These illustrate scavengers in the suspected area which eat infected dead body of animals contributing to the effort of reducing the expansion of disease. In addition, numerical comparison analysis with four distinct control strategies is carried out. Our findings show that each control technique has its own influence on reducing the total number of infections in the human and animal populations. The cumulative impact of all control measures is found to be extremely effective in lowering the prevalence of the disease.
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来源期刊
CiteScore
2.80
自引率
12.50%
发文量
31
审稿时长
1 months
期刊介绍: The Journal of Biological Systems is published quarterly. The goal of the Journal is to promote interdisciplinary approaches in Biology and in Medicine, and the study of biological situations with a variety of tools, including mathematical and general systems methods. The Journal solicits original research papers and survey articles in areas that include (but are not limited to): Complex systems studies; isomorphies; nonlinear dynamics; entropy; mathematical tools and systems theories with applications in Biology and Medicine. Interdisciplinary approaches in Biology and Medicine; transfer of methods from one discipline to another; integration of biological levels, from atomic to molecular, macromolecular, cellular, and organic levels; animal biology; plant biology. Environmental studies; relationships between individuals, populations, communities and ecosystems; bioeconomics, management of renewable resources; hierarchy theory; integration of spatial and time scales. Evolutionary biology; co-evolutions; genetics and evolution; branching processes and phyllotaxis. Medical systems; physiology; cardiac modeling; computer models in Medicine; cancer research; epidemiology. Numerical simulations and computations; numerical study and analysis of biological data. Epistemology; history of science. The journal will also publish book reviews.
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