塞克硝唑和顺势疗法在犬贾第鞭毛虫病控制中的应用

Pub Date : 2020-09-01 DOI:10.21897/rmvz.2004
Patrícia Glombowsky, Gabriela Campigotto, Maiara Sulzbach-Marchiori, Jorge A. Favaretto, Gabriela Miotto-Galli, A. S. Da silva
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引用次数: 0

摘要

感染贾第鞭毛虫的狗腹泻持续数天,甚至在治疗后也是如此。我们使用两种不同的方法治疗犬贾第虫病:单独使用抗原生动物塞克硝唑治疗;和塞克硝唑加一种顺势疗法产品,用于控制狗腹泻。治疗一:10只比格犬出现严重腹泻的临床症状。它们的粪便显示出大量与贾第鞭毛虫一致的囊肿。因此,我们用塞克硝唑(10 mg/kg,单剂量)口服治疗这些狗。治疗五天后,所有狗的贾第鞭毛虫均为阴性。治疗二:三个月后,同样的十只比格犬再次出现腹泻。收集粪便,发现所有狗都有贾第鞭毛虫。这一次,我们用抗原生动物(塞克硝唑,10 mg/kg剂量)与商业顺势疗法药物联合治疗腹泻(3 g剂量/只,间隔12小时)。我们发现,需要三到五个顺势疗法剂量才能使所有狗的粪便得分正常。治疗5天后,粪便样本具有正常稠度,贾第鞭毛虫呈阴性。这是首次使用塞克硝唑控制犬贾第鞭毛虫病,并使用顺势疗法药物预防腹泻。
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Use of secnidazole and homeopathy for giardiasis control in dogs
Dogs with Giardia infections have diarrhea that persists for days, even after treatment. We managed canine giardiasis using two distinct approaches: treatment with the antiprotozoan secnidazole alone; and secnidazole plus a homeopathic product that is indicated for control of diarrhea in dogs. Treatment I: Ten beagle dogs showed clinical signs of severe diarrhea. Their feces revealed large numbers of cysts consistent with Giardia sp. Therefore, we treated the dogs with secnidazole (10 mg/kg, single dose) given orally. Five days after treatment, all dogs were negative for Giardia spp. Treatment II: Three months later, the same ten Beagles again presented with diarrhea. Feces were collected, revealing Giardia sp. in all dogs. This time, we treated them with an antiprotozoan (secnidazole, 10 mg/kg dose) combined with a commercial homeopathic drug for diarrhea control (3 g dose/animal at 12 h interval). We found that three to five homeopathic doses were needed to achieve normal fecal scores in all dogs. After 5 days of treatment, stool samples had normal consistency and were negative for Giardia. This is the first record of using secnidazole to control canine giardiasis associated with homeopathic drugs to prevent diarrhea.
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