{"title":"减肥手术后患者与非手术对照组身体成分变量的比较。","authors":"Sirinrat Tangjittrong, Suthep Udomsawaengsup, Patchaya Boonchaya-Anant","doi":"10.1177/11795514231206731","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Since bariatric surgery results in massive weight loss, it may be associated with a disproportionate decrease in lean body mass.</p><p><strong>Objective: </strong>To evaluate body composition in post-bariatric surgery patients who had a successful weight loss at 12 months (>50% excess weight loss) with comparisons to healthy controls who were matched for age, sex and BMI.</p><p><strong>Methods: </strong>This is an observational analytic study using data from post-bariatric surgery patients who had laparoscopic Roux-en-Y gastric bypass (RYGB) or laparoscopic sleeve gastrectomy (SG) at King Chulalongkorn Memorial Hospital. Patients who had percentage excessive weight loss (%EWL) >50% and achieved a BMI of <30 kg/m<sup>2</sup> within 12 months after the surgery were included. Non-operative healthy controls matched for sex, age, and BMI (1:1) were recruited. The 12-month post-bariatric surgery BMI was used to match the BMI of the control subjects. A single bioelectrical impedance analysis (BIA) (Inbody 770) machine was used for the entire study.</p><p><strong>Results: </strong>Sixty participants were included in this study. There are 30 post-bariatric surgery patients (female n = 19, male n = 11) and 30 non-operative controls (female n = 19, male n = 11). The 12-month post-bariatric surgery patients had lower percentage of body fat (PBF) (30.6% vs 35.9%, <i>P</i>-value .001) and trunk fat mass (10.3 vs 12.4 kg, <i>P</i>-value .04) than non-operative controls. The 12-month post-bariatric surgery patients also were found to have more soft lean mass (SLM) (47.7 vs 39.9 kg, <i>P</i>-value .001), fat free mass (FFM) (51.1 vs 42.3 kg, <i>P</i>-value .001), skeletal muscle mass (SMM) (27.5 vs 23 kg, <i>P</i>-value .003), and trunk lean mass (21.2 vs 19 kg, <i>P</i>-value .02).</p><p><strong>Conclusion: </strong>Despite the significant reductions in all body composition variables in post-bariatric surgery patients at 12-month follow-up, both fat free mass and skeletal muscle mass were found to be higher in the surgical patients compared to the control group.</p><p><strong>Clinical trials: </strong>Thai Clinical Trials Registry, https://thaiclinicaltrials.org/ID:TCTR20200223003.</p>","PeriodicalId":44715,"journal":{"name":"Clinical Medicine Insights-Endocrinology and Diabetes","volume":"16 ","pages":"11795514231206731"},"PeriodicalIF":2.7000,"publicationDate":"2023-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f3/22/10.1177_11795514231206731.PMC10583510.pdf","citationCount":"0","resultStr":"{\"title\":\"Comparison of Body Composition Variables between Post-Bariatric Surgery Patients and Non-Operative Controls.\",\"authors\":\"Sirinrat Tangjittrong, Suthep Udomsawaengsup, Patchaya Boonchaya-Anant\",\"doi\":\"10.1177/11795514231206731\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Since bariatric surgery results in massive weight loss, it may be associated with a disproportionate decrease in lean body mass.</p><p><strong>Objective: </strong>To evaluate body composition in post-bariatric surgery patients who had a successful weight loss at 12 months (>50% excess weight loss) with comparisons to healthy controls who were matched for age, sex and BMI.</p><p><strong>Methods: </strong>This is an observational analytic study using data from post-bariatric surgery patients who had laparoscopic Roux-en-Y gastric bypass (RYGB) or laparoscopic sleeve gastrectomy (SG) at King Chulalongkorn Memorial Hospital. Patients who had percentage excessive weight loss (%EWL) >50% and achieved a BMI of <30 kg/m<sup>2</sup> within 12 months after the surgery were included. Non-operative healthy controls matched for sex, age, and BMI (1:1) were recruited. The 12-month post-bariatric surgery BMI was used to match the BMI of the control subjects. A single bioelectrical impedance analysis (BIA) (Inbody 770) machine was used for the entire study.</p><p><strong>Results: </strong>Sixty participants were included in this study. There are 30 post-bariatric surgery patients (female n = 19, male n = 11) and 30 non-operative controls (female n = 19, male n = 11). The 12-month post-bariatric surgery patients had lower percentage of body fat (PBF) (30.6% vs 35.9%, <i>P</i>-value .001) and trunk fat mass (10.3 vs 12.4 kg, <i>P</i>-value .04) than non-operative controls. The 12-month post-bariatric surgery patients also were found to have more soft lean mass (SLM) (47.7 vs 39.9 kg, <i>P</i>-value .001), fat free mass (FFM) (51.1 vs 42.3 kg, <i>P</i>-value .001), skeletal muscle mass (SMM) (27.5 vs 23 kg, <i>P</i>-value .003), and trunk lean mass (21.2 vs 19 kg, <i>P</i>-value .02).</p><p><strong>Conclusion: </strong>Despite the significant reductions in all body composition variables in post-bariatric surgery patients at 12-month follow-up, both fat free mass and skeletal muscle mass were found to be higher in the surgical patients compared to the control group.</p><p><strong>Clinical trials: </strong>Thai Clinical Trials Registry, https://thaiclinicaltrials.org/ID:TCTR20200223003.</p>\",\"PeriodicalId\":44715,\"journal\":{\"name\":\"Clinical Medicine Insights-Endocrinology and Diabetes\",\"volume\":\"16 \",\"pages\":\"11795514231206731\"},\"PeriodicalIF\":2.7000,\"publicationDate\":\"2023-10-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f3/22/10.1177_11795514231206731.PMC10583510.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Medicine Insights-Endocrinology and Diabetes\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/11795514231206731\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2023/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"ENDOCRINOLOGY & METABOLISM\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Medicine Insights-Endocrinology and Diabetes","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/11795514231206731","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}
引用次数: 0
摘要
背景：由于减肥手术会导致大量体重减轻，这可能与瘦体重的不成比例的减少有关。目的：评估12岁时成功减肥的减肥手术后患者的身体成分 方法：这是一项观察性分析研究，使用了在朱拉隆功国王纪念医院接受腹腔镜Roux-en-Y胃旁路术（RYGB）或腹腔镜袖状胃切除术（SG）的减肥手术后患者的数据。体重过度减轻百分比（%EWL）>50%且BMI在12以内达到2的患者 包括手术后数月。招募性别、年龄和BMI（1:1）匹配的非手术健康对照组。减肥手术后12个月的BMI用于匹配对照受试者的BMI。整个研究使用单个生物电阻抗分析（BIA）（Inbody 770）机器。结果：60名参与者被纳入本研究。有30名减肥手术后患者（女性 = 19，男性n = 11） 和30名非手术对照组（女性n = 19，男性n = 11） 。减肥手术后12个月的患者体脂百分比（PBF）（30.6%对35.9%，P值.001）和躯干脂肪量（10.3对12.4）较低 kg，P值.04）。减肥手术后12个月的患者也被发现有更柔软的瘦块（SLM）（47.7比39.9 kg，P值.001），无脂肪质量（FFM）（51.1 vs 42.3 kg，P值.001），骨骼肌质量（SMM）（27.5 vs 23 kg，P值.003）和躯干瘦质量（21.2 vs 19 kg，P值.02）。结论：尽管在12个月的随访中，减肥手术后患者的所有身体成分变量都显著减少，但与对照组相比，手术患者的无脂肪质量和骨骼肌质量都更高。临床试验：泰国临床试验注册处，https://thaiclinicaltrials.org/ID:TCTR20200223003.
Comparison of Body Composition Variables between Post-Bariatric Surgery Patients and Non-Operative Controls.
Background: Since bariatric surgery results in massive weight loss, it may be associated with a disproportionate decrease in lean body mass.
Objective: To evaluate body composition in post-bariatric surgery patients who had a successful weight loss at 12 months (>50% excess weight loss) with comparisons to healthy controls who were matched for age, sex and BMI.
Methods: This is an observational analytic study using data from post-bariatric surgery patients who had laparoscopic Roux-en-Y gastric bypass (RYGB) or laparoscopic sleeve gastrectomy (SG) at King Chulalongkorn Memorial Hospital. Patients who had percentage excessive weight loss (%EWL) >50% and achieved a BMI of <30 kg/m2 within 12 months after the surgery were included. Non-operative healthy controls matched for sex, age, and BMI (1:1) were recruited. The 12-month post-bariatric surgery BMI was used to match the BMI of the control subjects. A single bioelectrical impedance analysis (BIA) (Inbody 770) machine was used for the entire study.
Results: Sixty participants were included in this study. There are 30 post-bariatric surgery patients (female n = 19, male n = 11) and 30 non-operative controls (female n = 19, male n = 11). The 12-month post-bariatric surgery patients had lower percentage of body fat (PBF) (30.6% vs 35.9%, P-value .001) and trunk fat mass (10.3 vs 12.4 kg, P-value .04) than non-operative controls. The 12-month post-bariatric surgery patients also were found to have more soft lean mass (SLM) (47.7 vs 39.9 kg, P-value .001), fat free mass (FFM) (51.1 vs 42.3 kg, P-value .001), skeletal muscle mass (SMM) (27.5 vs 23 kg, P-value .003), and trunk lean mass (21.2 vs 19 kg, P-value .02).
Conclusion: Despite the significant reductions in all body composition variables in post-bariatric surgery patients at 12-month follow-up, both fat free mass and skeletal muscle mass were found to be higher in the surgical patients compared to the control group.
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