加纳一名单侧膈肌事件和HIV 1型感染患者的耐碳青霉烯鲍曼不动杆菌血流感染。

IF 1 Q4 INFECTIOUS DISEASES Case Reports in Infectious Diseases Pub Date : 2023-10-12 eCollection Date: 2023-01-01 DOI:10.1155/2023/9930291
Yvonne Ayerki Nartey, Augustine Boakye Donkor, Ampem Darko Jnr Siaw, Oluwayemisi Esther Ekor, Bashiru Babatunde Jimah
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引用次数: 0

摘要

耐碳青霉烯的鲍曼不动杆菌感染是世界卫生组织最优先考虑的病原体,由于住院患者死亡率的增加,它引起了人们越来越多的关注。膈神经麻痹是C3、C4和C5神经根带状疱疹感染的罕见并发症。我们报告了一例加纳患者的血液中碳青霉烯耐药性鲍曼不动杆菌感染病例,该患者患有HIV 1型感染和多种危险因素,包括可能继发于带状疱疹感染引起的膈神经麻痹的单侧膈肌事件和压迫性肺不张,从而导致反复住院和入住ICU。在这种情况下,我们强调LMIC的临床医生需要意识到CRAB,以便在资源有限的环境中倡导循证药物的可用性,以进行适当的治疗。此外,我们还说明了高怀疑指数对感染碳青霉烯类耐药生物(如鲍曼不动杆菌)的重要性,并强调了带状疱疹感染的一种罕见而严重的并发症,表现为膈神经麻痹和随后的膈肌事件。
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Carbapenem-Resistant Acinetobacter baumannii Bloodstream Infection in a Ghanaian Patient with Unilateral Diaphragmatic Eventration and HIV Type 1 Infection.

Carbapenem-resistant Acinetobacter baumannii infection is a critically prioritized pathogen by the World Health Organization and a cause for growing concern due to increased mortality among hospitalised patients. Phrenic nerve palsy is a rare complication of herpes zoster infection of the C3, C4, and C5 nerve roots. We present a case of bloodstream carbapenem-resistant A. baumannii infection in a Ghanaian patient with HIV type 1 infection and multiple risk factors, including unilateral diaphragmatic eventration with compression atelectasis likely secondary to phrenic nerve palsy due to herpes zoster infection, consequently leading to recurrent hospital and ICU admission. In this case, we emphasize the need for clinicians in LMICs to be aware of CRAB, in order to advocate for the availability of evidence-based medicines in resource-limited settings for appropriate treatment. In addition, we illustrate the importance of a high index of suspicion for infection with carbapenem-resistant organisms such as A. baumannii and highlight a rare and severe complication of herpes zoster infection in the form of phrenic nerve palsy and consequent diaphragmatic eventration.

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审稿时长
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