通过紧凑的基于csrr的微波传感器识别颈动脉斑块组成

IF 5.6 4区医学 Q1 ENGINEERING, BIOMEDICAL Irbm Pub Date : 2023-04-01 DOI:10.1016/j.irbm.2022.09.001

R. Shahbaz , F. Deshours , G. Alquie , H. Kokabi , F. Koskas , I. Brocheriou , G. Le Naour , C. Hannachi , J.-M. Davaine

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引用次数: 0

摘要

目的本研究旨在确定颈动脉粥样硬化斑块的介电常数，并使用基于CSRR的微波传感器对其进行分类。材料和方法一个2.3 GHz的互补分裂环谐振器（CSRR）测量了33个动脉内膜切除术后获得的颈动脉斑块样本。HFSS软件模拟用于证实测量结果。同时进行组织学分析以对斑块进行分类。结果组织学鉴定的危险颈动脉斑块的介电常数远高于低危钙化颈动脉斑块。微波数据与模拟有关。结论目前在离体颈动脉斑块上进行的研究表明，传感器能够区分不同成分的斑块。钙化的低风险斑块显示出与危险的软斑块不同的价值。需要对33个样本进行进一步的统计相关性。验证后，将设计并测试体内原型。

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Identification of Carotid Plaques Composition Through a Compact CSRR-Based Microwave Sensor

Objectives

This study aims to identify the dielectric constant of the carotid atherosclerotic plaques and categorise them using a CSRR based microwave sensor.

Material and methods

A Complementary Split Ring Resonator (CSRR) at 2.3 GHz measured 33 samples of carotid plaques obtained after endarterectomy. HFSS software simulations were employed to substantiate the measurements. Histological analyses were performed simultaneously to classify the plaques.

Results

The constant dielectric of dangerous carotid plaques identified by histology was much higher than that of low-risk calcified carotid plaques. Microwave data were pertinent to the simulations.

Conclusion

The current study, performed on ex-vivo carotid plaques, illustrates the sensor's ability to differentiate plaques with diverse components. Calcified low-risk plaques displayed distinct values from dangerous soft plaques. Further statistical correlation of the 33 samples is required. After validation, an in-vivo prototype will be designed and tested.

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来源期刊

Irbm ENGINEERING, BIOMEDICAL-

CiteScore

10.30

自引率

4.20%

发文量

审稿时长

57 days

期刊介绍： IRBM is the journal of the AGBM (Alliance for engineering in Biology an Medicine / Alliance pour le génie biologique et médical) and the SFGBM (BioMedical Engineering French Society / Société française de génie biologique médical) and the AFIB (French Association of Biomedical Engineers / Association française des ingénieurs biomédicaux). As a vehicle of information and knowledge in the field of biomedical technologies, IRBM is devoted to fundamental as well as clinical research. Biomedical engineering and use of new technologies are the cornerstones of IRBM, providing authors and users with the latest information. Its six issues per year propose reviews (state-of-the-art and current knowledge), original articles directed at fundamental research and articles focusing on biomedical engineering. All articles are submitted to peer reviewers acting as guarantors for IRBM''s scientific and medical content. The field covered by IRBM includes all the discipline of Biomedical engineering. Thereby, the type of papers published include those that cover the technological and methodological development in: -Physiological and Biological Signal processing (EEG, MEG, ECG…)- Medical Image processing- Biomechanics- Biomaterials- Medical Physics- Biophysics- Physiological and Biological Sensors- Information technologies in healthcare- Disability research- Computational physiology- …