一种新型双凹曲面切削刃活检针

IF 5.6 4区 医学 Q1 ENGINEERING, BIOMEDICAL Irbm Pub Date : 2023-10-01 DOI:10.1016/j.irbm.2023.100783
Chi-Lun Lin , Yu-Ming Huang , Zheng-Yan Luo , Yu-Hsien Hsieh
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引用次数: 0

摘要

背景真空辅助活检是一种微创采样技术,它依赖于旋转切割作为主要的组织回收方法。这种疾病的精确诊断需要大量未破碎的样本,这些样本会受到活检针切割力的影响。目的本研究提出了一种新型的双凹面弯曲刀刃针头设计,更适合旋转针头切割。我们的目标是优化设计,以便可以用最小的切割力提取大的、未损坏的样本。材料与方法采用田口法设计五因素实验。进行了包括旋转针头插入和组织取样的实验,以分别检查这些变量对切割力和取样质量的影响。分析了切削力与取样质量的关系。结果对于针头插入,在设计空间内的最佳设计显示切割力从1.2107 N显著提高到0.1888 N。此外,在相同的针头速度下,优化的双凹曲针优于钝针,显示切割力降低了24.4%(0.1888 vs.0.2496 N)。增加旋转平移比或插入速度将允许提取更大的样品(重量增加至21.95%,总长度增加至17.21%),但也可能增加旋转速度,导致样品碎裂。为了同时提高采样质量和切割力,建议使用更高的K值、更大的旋转平移比和更慢的插入速度。根据本研究中检查的条件,最佳针头配置应包括K值为0.2、旋转平移比为8、插入速度为1mm/s的锋利切削刃。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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A Novel Biopsy Needle with Double Concave-Curved Cutting Edges

Background

Vacuum-assisted biopsy is a minimally invasive sampling technique that relies on rotational cutting as a major tissue retrieving method. A precise diagnosis of the disease requires large, uncrushed samples, which are impacted by the cutting force of the biopsy needle.

Objectives

This study proposes a novel needle design with double-concave-curved cutting edges, which is more suited for rotational needle cutting. We aimed to optimize the design so that large, undamaged samples could be extracted with minimal cutting force.

Materials and Methods

Five-factor experiments were designed using the Taguchi method. Experiments involving rotational needle insertion and tissue sampling were conducted to examine the effects of these variables on the cutting force and sampling quality, respectively. The relationship between the cutting force and sampling quality was analyzed.

Results

For needle insertion, the optimal design within the design space demonstrated a marked improvement in cutting force from 1.2107 to 0.1888 N. Furthermore, the optimized double concave-curved needle outperformed the blunt needle under the same needle speeds, showing a 24.4% reduction in cutting force (0.1888 vs. 0.2496 N). Increasing rotation-translation ratio or insertion speed would allow for extracting a larger sample (increased up to 21.95% in weight and 17.21% in total length) but may also increase the rotation speed, resulting in sample fragmentation. To simultaneously improve sampling quality and cutting force, a higher K value, larger rotation-translation ratio, and slower insertion speed are suggested. Based on the conditions examined in this study, the optimal needle configuration should include a sharpened cutting edge with a K value of 0.2, a rotation-translation ratio of 8, and an insertion speed of 1 mm/s.

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来源期刊
Irbm
Irbm ENGINEERING, BIOMEDICAL-
CiteScore
10.30
自引率
4.20%
发文量
81
审稿时长
57 days
期刊介绍: IRBM is the journal of the AGBM (Alliance for engineering in Biology an Medicine / Alliance pour le génie biologique et médical) and the SFGBM (BioMedical Engineering French Society / Société française de génie biologique médical) and the AFIB (French Association of Biomedical Engineers / Association française des ingénieurs biomédicaux). As a vehicle of information and knowledge in the field of biomedical technologies, IRBM is devoted to fundamental as well as clinical research. Biomedical engineering and use of new technologies are the cornerstones of IRBM, providing authors and users with the latest information. Its six issues per year propose reviews (state-of-the-art and current knowledge), original articles directed at fundamental research and articles focusing on biomedical engineering. All articles are submitted to peer reviewers acting as guarantors for IRBM''s scientific and medical content. The field covered by IRBM includes all the discipline of Biomedical engineering. Thereby, the type of papers published include those that cover the technological and methodological development in: -Physiological and Biological Signal processing (EEG, MEG, ECG…)- Medical Image processing- Biomechanics- Biomaterials- Medical Physics- Biophysics- Physiological and Biological Sensors- Information technologies in healthcare- Disability research- Computational physiology- …
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