evolocmab作为lorlatinib继发性血脂异常的治疗

Laura Pérez Alonso , Raquel Cervera Calero , María Ángeles Campos Fernández de Sevilla , Miguel Ángel Moreno Palanco , Jorge Francisco Gómez Cerezo
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引用次数: 0

摘要

抗PCSK9单克隆抗体降低了动脉粥样硬化性心血管疾病患者发生心血管事件的风险。然而,其在与洛拉替尼相关的高脂血症中的应用尚未得到描述,洛拉替尼是一种第三代ALK酪氨酸kinasa抑制剂,被批准用于治疗ALK阳性非小细胞肺癌癌症。
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Evolocumab como tratamiento de la dislipemia secundaria a lorlatinib

Anti-PCSK9 monoclonal antibodies have reduced the risk of cardiovascular events in patients with atheroesclerosis cardiovascular disease. However, its use has not been described in hyperlipidemia associated with lorlatinib, a third-generation ALK tyrosin kinasa inhibitor approved as treatment for ALK-positive non-small cell lung cancer.

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