covid后颌骨骨坏死(PCONJ)是否伪装成骨髓炎?最大的单中心报告13例

Mohd Aswad Khan, Tabishur Rahman, Sajjad Abdur Rahman, Ghulam Sarwar Hashmi, Md Kalim Ansari, Mohammad Danish, Mohammad Arman, Rizwan Ahmad, Wasim Ahmad
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引用次数: 0

摘要

目的本研究旨在确定新冠肺炎感染与颌骨坏死之间的相关性,并确定可能与该疾病发展相关的危险因素。我们研究的另一个目的是确定颌面部骨坏死是新冠肺炎患者的早期并发症还是晚期并发症。材料和方法这是一项为期两年的回顾性研究。评估了有严重新冠肺炎和类固醇治疗史的患者后来出现颌骨坏死的病例记录。结果13例患者年龄在8岁至70岁之间。新冠肺炎后21个月出现骨坏死。大多数病例涉及上颌骨,一例为双颌受累,一例表现为孤立性下颌受累。6名患者患有糖尿病,11名患者有拔牙等挑衅性牙科治疗史。结论COVID后凝血障碍、类固醇给药和刺激性牙科治疗三者可能导致颌骨坏死,这种坏死可能出现在没有预先存在的全身性疾病的患者中,最迟可能在新冠肺炎后21个月出现。
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Is post-COVID osteonecrosis of jaw (PCONJ) Masquerading as osteomyelitis ? A largest unicentric report of 13 cases

Objective

The purpose of this study was to ascertain the correlation between COVID-19 infection and jaw osteonecrosis, along with the identification of risk factors that could be associated with the development of the condition. Another aim of our study is to establish whether maxillofacial osteonecrosis is an early or late complication seen in COVID-19 patients.

Material and method

This was a retrospective study conducted over a period of two years. Case records of patients with a history of severe COVID and steroid treatment who later developed jaw osteonecrosis were evaluated.

Result

13 patients with an age range from 8 years to 70 years were identified. Osteonecrosis was seen as late as 21 months after COVID-19. The majority of the cases involved maxilla, one case was of bi-jaw involvement, and one case presented with isolated mandibular involvement. 6 patients were diabetic and 11 patients gave a history of provocative dental treatment like extraction.

Conclusion

A triad of post-COVID coagulopathy, steroid administration, and a provocative dental treatment may contribute to jaw osteonecrosis which may be seen in patients without pre-existing systemic illness and may present as late as 21 months after COVID-19.

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