Neurosyphilis-an uncommon cause of neurogenic lower urinary tract dysfunction

In the modern era, neurosyphilis is rare and its effects on the lower urinary tract are poorly understood. Two cases of neurosyphilis with resultant bladder dysfunction are presented, and the relevant literature on neurosyphilis is reviewed. For our patients, urodynamic studies revealed low-capacity bladders associated with detrusor overactivity in both cases, one with a clinical diagnosis of urge incontinence and the other with urinary retention. These cases highlight the importance of early assessment of urinary function in patients with neurosyphilis and the role of urodynamics in guiding appropriate management.