Managing Risk of Dysplasia and Colorectal Cancer in Inflammatory Bowel Disease

Mitigating colorectal cancer (CRC) risk is a pillar in caring for patients with inflammatory bowel disease (IBD). Over the last decade, there have been significant advances in understanding the natural history of colitis-associated dysplasia (CAD) and its management. The identification of patient- and disease-specific risk factors has enabled a tailored approach to initiating colonoscopy screening and surveillance programs. Improved video endoscopy systems and the development of advanced endoscopic resection techniques have evolved the role of endoscopy in CAD. Modern-era endoscopic instruments can better detect and effectively intervene with CAD, reducing CRC risk. As a result, the last decade has brought forth substantial changes to how endoscopic technologies are applied to IBD surveillance. This review will go over the latest updates in the stratification and management of CAD and CRC risk for patients with IBD, as well as discuss the exciting future in this topic area.