Ventricular septal rupture in a premature infant with incomplete Kawasaki disease: An unusual complication

Kawasaki disease and the associated complication of Ventricular Septal Rupture are extremely rare in neonates, particularly among premature infants. We report a case of a premature infant who was diagnosed with incomplete Kawasaki disease after an echocardiogram incidentally demonstrated a coronary artery aneurysm. The patient developed Ventricular Septal Rupture secondary to myocardial infarction seven months after the onset of the disease. This case highlighted the importance of coronary artery screening in a febrile neonatal patient who did not respond to multiple courses of antibiotics. Due to the rarity of the disease in neonates and the complications, the management of Ventricular Septal Rupture postneonatal Kawasaki disease is challenging as there is no consensus regarding treatment.