Advancements in precision nutrition: Steady-state targeted delivery of food functional factors for nutrition intervention of chronic diseases

Nutritional intervention plays a significant role in controlling the progression of chronic diseases and improving therapeutic outcomes. Food functional factors are bioactive compounds found in foods that can regulate body's physiological functions and support health by regulating enzyme activity and metabolic pathways. However, many food functional factors face significant challenges in terms of their bioavailability, stability, and solubility. Furthermore, individual differences in genetics, metabolism, lifestyle, and environmental factors can significantly influence nutrient requirements and intake. Therefore, personalized nutritional intervention and precise delivery based on individual characteristics are necessary to achieve precision nutrition. Steady-state targeted delivery systems have emerged as a promising approach to improving the precise nutritional interventions for chronic diseases. In this review, we explore the latest progress in the steady-state targeted delivery of food functional components for precision nutrition. We discuss the challenges and opportunities associated with these systems as well as their potential applications in managing chronic diseases and improving health outcomes. The review highlights the significant role that steady-state targeted delivery systems can play in advancing precision nutrition and thus promoting better health for individuals.