Front Cover: Behavior of Constitutional Dynamic Networks: Competition, Selection, Self-sorting in Cryptate Systems (ChemistryEurope 1/2023)

Reaction networks of dynamic combinatorial libraries (DCLs) of cryptates were examined to better understand self-sorting, dynamic competition, and co-evolution processes. These findings, reported by Jean-Marie Lehn and co-workers in their Research Article, indicate that an increase in complexity (multiplicity and connectivity) of a system may, under dynamic competition, result in “simplexity”—a simplification of the output of the system—expressed in the self-sorting of its constituents.