{"title":"牙齿漂白剂对牙本质原位抗疲劳性能的影响。","authors":"J M Fitzgerald, G De Souza, L Tam","doi":"10.2341/22-093-C","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Negative effects of bleaching on dentin have previously been reported in vitro.</p><p><strong>Objective: </strong>The purpose of this study was to determine the effect of carbamide peroxide bleaching on dentin fatigue resistance using a clinically relevant in situ model.</p><p><strong>Methods and materials: </strong>Following research ethics board approval, 60 human teeth requiring extraction were collected. Sterilized human dentin specimens were cut (1.2x1.2x10 mm) and secured into customized bleaching trays to be used by study participants. Participants were randomly assigned to either bleach (10% carbamide peroxide, n=23) or control (gel without bleach, n=26) treatment groups. Treatment was applied to the bleaching trays and worn overnight by participants for 14 days. After treatment completion, dentin specimens were removed from the bleaching trays and subjected to fatigue testing (10 N, 3 mm/s, 2x105 cycles) while submerged in artificial saliva. Kaplan-Meier survival analysis was conducted to compare the number of cycles to failure during fatigue testing in both groups. A log rank test was run to determine if there were differences in the survival distribution between the two groups (α<0.05).</p><p><strong>Results: </strong>The median number of cycles to failure was 352 ± 202 and 760 ± 644 for the bleach and control groups, respectively. The survival distributions for the two groups were significantly different (p=0.020). Dentin fatigue resistance was significantly lower in the bleach group compared to the control.</p><p><strong>Conclusions: </strong>Direct bleaching of human dentin using an at-home tray bleaching protocol in situ reduced dentin fatigue resistance. This has implications for tooth fracture risk and longevity.</p>","PeriodicalId":19502,"journal":{"name":"Operative dentistry","volume":null,"pages":null},"PeriodicalIF":1.4000,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Effect of Tooth Bleach on Dentin Fatigue Resistance in Situ.\",\"authors\":\"J M Fitzgerald, G De Souza, L Tam\",\"doi\":\"10.2341/22-093-C\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Negative effects of bleaching on dentin have previously been reported in vitro.</p><p><strong>Objective: </strong>The purpose of this study was to determine the effect of carbamide peroxide bleaching on dentin fatigue resistance using a clinically relevant in situ model.</p><p><strong>Methods and materials: </strong>Following research ethics board approval, 60 human teeth requiring extraction were collected. Sterilized human dentin specimens were cut (1.2x1.2x10 mm) and secured into customized bleaching trays to be used by study participants. Participants were randomly assigned to either bleach (10% carbamide peroxide, n=23) or control (gel without bleach, n=26) treatment groups. Treatment was applied to the bleaching trays and worn overnight by participants for 14 days. After treatment completion, dentin specimens were removed from the bleaching trays and subjected to fatigue testing (10 N, 3 mm/s, 2x105 cycles) while submerged in artificial saliva. Kaplan-Meier survival analysis was conducted to compare the number of cycles to failure during fatigue testing in both groups. A log rank test was run to determine if there were differences in the survival distribution between the two groups (α<0.05).</p><p><strong>Results: </strong>The median number of cycles to failure was 352 ± 202 and 760 ± 644 for the bleach and control groups, respectively. The survival distributions for the two groups were significantly different (p=0.020). Dentin fatigue resistance was significantly lower in the bleach group compared to the control.</p><p><strong>Conclusions: </strong>Direct bleaching of human dentin using an at-home tray bleaching protocol in situ reduced dentin fatigue resistance. This has implications for tooth fracture risk and longevity.</p>\",\"PeriodicalId\":19502,\"journal\":{\"name\":\"Operative dentistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2023-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Operative dentistry\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2341/22-093-C\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Operative dentistry","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2341/22-093-C","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Effect of Tooth Bleach on Dentin Fatigue Resistance in Situ.
Background: Negative effects of bleaching on dentin have previously been reported in vitro.
Objective: The purpose of this study was to determine the effect of carbamide peroxide bleaching on dentin fatigue resistance using a clinically relevant in situ model.
Methods and materials: Following research ethics board approval, 60 human teeth requiring extraction were collected. Sterilized human dentin specimens were cut (1.2x1.2x10 mm) and secured into customized bleaching trays to be used by study participants. Participants were randomly assigned to either bleach (10% carbamide peroxide, n=23) or control (gel without bleach, n=26) treatment groups. Treatment was applied to the bleaching trays and worn overnight by participants for 14 days. After treatment completion, dentin specimens were removed from the bleaching trays and subjected to fatigue testing (10 N, 3 mm/s, 2x105 cycles) while submerged in artificial saliva. Kaplan-Meier survival analysis was conducted to compare the number of cycles to failure during fatigue testing in both groups. A log rank test was run to determine if there were differences in the survival distribution between the two groups (α<0.05).
Results: The median number of cycles to failure was 352 ± 202 and 760 ± 644 for the bleach and control groups, respectively. The survival distributions for the two groups were significantly different (p=0.020). Dentin fatigue resistance was significantly lower in the bleach group compared to the control.
Conclusions: Direct bleaching of human dentin using an at-home tray bleaching protocol in situ reduced dentin fatigue resistance. This has implications for tooth fracture risk and longevity.
期刊介绍：
Operative Dentistry is a refereed, international journal published bi-monthly and distributed to subscribers in over 50 countries. In 2012, we printed 84 articles (672 pages). Papers were submitted by authors from 45 countries, in the categories of Clinical Research, Laboratory Research, Clinical Techniques/Case Presentations and Invited Papers, as well as Editorials and Abstracts.
One of the strong points of our journal is that our current publication time for accepted manuscripts is 4 to 6 months from the date of submission. Clinical Techniques/Case Presentations have a very quick turnaround time, which allows for very rapid publication of clinical based concepts. We also provide color for those papers that would benefit from its use.
The journal does not accept any advertising but you will find postings for faculty positions. Additionally, the journal also does not rent, sell or otherwise allow its subscriber list to be used by any other entity
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