由根霉小孢子引起的播散性肺和肾毛霉菌病致死病例。

IF 1.5 4区 医学 Q4 INFECTIOUS DISEASES Revista Do Instituto De Medicina Tropical De Sao Paulo Pub Date : 2023-10-20 eCollection Date: 2023-01-01 DOI:10.1590/S1678-9946202365054
Liuyang Hu, Xingchun Chen
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引用次数: 0

摘要

鼻脑和肺毛霉菌病是毛霉菌病的主要表现;然而,与肾毛霉菌病相关的播散性肺部疾病很少报道。在本文中,我们报告了一例罕见的致命病例,由微孢子根霉引起的播散性肺和肾毛霉菌病发生在一名50岁的男子身上,他患有控制不佳的高血压、2型糖尿病,并长期使用皮质类固醇治疗其反复发作的痛风性关节炎。在该患者中,皮质类固醇的使用和控制不佳的糖尿病被认为是其播散性毛霉菌病以及急性肾功能障碍的潜在风险因素,这表明在糖尿病控制不佳和宿主免疫功能受损的住院患者中,临床上需要怀疑播散性肺和肾毛霉菌病。
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A fatal case of disseminated pulmonary and renal mucormycosis caused by Rhizopus microspores.

Rhinocerebral and pulmonary mucormycosis are the main manifestations of mucormycosis; however, disseminated pulmonary associated with renal mucormycosis is rarely reported. In this paper, we report a rare fatal case of disseminated pulmonary and renal mucormycosis caused by Rhizopus microsporus in a 50-year-old man with poorly controlled hypertension, type 2 diabetes, and prolonged use of corticosteroids for the treatment of his reiterative gouty arthritis. In this patient, the use of corticosteroids and poorly controlled diabetes were considered underlying risk factor for his disseminated mucormycosis, along with acute renal dysfunction, suggesting the need for clinical suspicion of disseminated pulmonary and renal mucormycosis in hospitalized patients with poorly controlled diabetes and immunocompromised host.

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来源期刊
CiteScore
3.60
自引率
5.30%
发文量
100
审稿时长
6-12 weeks
期刊介绍: The Revista do Instituto de Medicina Tropical de São Paulo (Journal of the São Paulo Institute of Tropical Medicine) is a journal devoted to research on different aspects of tropical infectious diseases. The journal welcomes original work on all infectious diseases, provided that data and results are directly linked to human health. The journal publishes, besides original articles, review articles, case reports, brief communications, and letters to the editor. The journal publishes manuscripts only in English. From 2016 on, the Revista do Instituto de Medicina Tropical de São Paulo (Journal of the São Paulo Institute of Tropical Medicine) is published online only, maintaining the free access. For more information visit: - http://www.scielo.br/rimtsp - http://www.imt.usp.br/revista-imt/
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