Danny Lam , Log Tung Lai , Ashish Agar , Tim Y-T. Lu , Minas T. Coroneo , Ian C. Francis
{"title":"颞动脉炎引起的右侧完全性视力丧失仅在左侧视力恶化后才被识别,需要最大限度的类固醇治疗和托西利珠单抗","authors":"Danny Lam , Log Tung Lai , Ashish Agar , Tim Y-T. Lu , Minas T. Coroneo , Ian C. Francis","doi":"10.1016/j.nerep.2022.100159","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Temporal Arteritis is the most common panarteritis in adults and typically affects elderly people, particularly women. This occlusive vasculitis is associated with at least 51 symptoms and signs and can result in bilateral blindness and potentially death from aortic root dilatation and rupture.</p></div><div><h3>Case Report</h3><p>This report demonstrates a case of Temporal Arteritis with bilateral, rapidly progressive arteritic anterior ischaemic optic neuropathy despite recommended high dose oral steroid therapy, with right eye blindness only recognised after left visual loss developed. The addition of tocilizumab was required for resolution of the symptoms.</p></div><div><h3>Conclusions</h3><p>It is essential to examine thoroughly all the parameters of visual function in a patient who has lost vision. Such an examination, especially in patients with TA, consists as a minimum of visual acuity, pupil reactions, confrontation fields and fundi in both eyes in every patient.</p></div>","PeriodicalId":100950,"journal":{"name":"Neuroimmunology Reports","volume":"3 ","pages":"Article 100159"},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Total right visual loss due to Temporal Arteritis recognised only after left visual deterioration, necessitating maximal steroid therapy and tocilizumab\",\"authors\":\"Danny Lam , Log Tung Lai , Ashish Agar , Tim Y-T. Lu , Minas T. Coroneo , Ian C. Francis\",\"doi\":\"10.1016/j.nerep.2022.100159\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Temporal Arteritis is the most common panarteritis in adults and typically affects elderly people, particularly women. This occlusive vasculitis is associated with at least 51 symptoms and signs and can result in bilateral blindness and potentially death from aortic root dilatation and rupture.</p></div><div><h3>Case Report</h3><p>This report demonstrates a case of Temporal Arteritis with bilateral, rapidly progressive arteritic anterior ischaemic optic neuropathy despite recommended high dose oral steroid therapy, with right eye blindness only recognised after left visual loss developed. The addition of tocilizumab was required for resolution of the symptoms.</p></div><div><h3>Conclusions</h3><p>It is essential to examine thoroughly all the parameters of visual function in a patient who has lost vision. Such an examination, especially in patients with TA, consists as a minimum of visual acuity, pupil reactions, confrontation fields and fundi in both eyes in every patient.</p></div>\",\"PeriodicalId\":100950,\"journal\":{\"name\":\"Neuroimmunology Reports\",\"volume\":\"3 \",\"pages\":\"Article 100159\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Neuroimmunology Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2667257X2200105X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Neuroimmunology Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2667257X2200105X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Total right visual loss due to Temporal Arteritis recognised only after left visual deterioration, necessitating maximal steroid therapy and tocilizumab
Background
Temporal Arteritis is the most common panarteritis in adults and typically affects elderly people, particularly women. This occlusive vasculitis is associated with at least 51 symptoms and signs and can result in bilateral blindness and potentially death from aortic root dilatation and rupture.
Case Report
This report demonstrates a case of Temporal Arteritis with bilateral, rapidly progressive arteritic anterior ischaemic optic neuropathy despite recommended high dose oral steroid therapy, with right eye blindness only recognised after left visual loss developed. The addition of tocilizumab was required for resolution of the symptoms.
Conclusions
It is essential to examine thoroughly all the parameters of visual function in a patient who has lost vision. Such an examination, especially in patients with TA, consists as a minimum of visual acuity, pupil reactions, confrontation fields and fundi in both eyes in every patient.