Zhibo Ma, Zheng Xiang, T. Luo, K. Lu, Zhibin Xu, Jia-Hua Chen, Zhen Yang
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Synthesis of functionalized quinolines via Ugi and Pd-catalyzed intramolecular arylation reactions.
Two types of quinoline scaffolds were constructed in a combinatorial format via the Ugi four-component reaction (U-4CR) and Pd-catalyzed intramolecular arylation reaction. The scope of this two-step synthetic sequence was examined from commercially available and synthetically accessible starting materials.
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