Thomas Schmidt, Orlin Belyaev, Waldemar Uhl, Christiane J Bruns
{"title":"[胰腺癌的外科治疗--有什么新进展？］","authors":"Thomas Schmidt, Orlin Belyaev, Waldemar Uhl, Christiane J Bruns","doi":"10.1007/s00104-022-01618-7","DOIUrl":null,"url":null,"abstract":"<p><p>The incidence of pancreatic ductal adenocarcinoma is continuously increasing and will become the second leading cause of cancer-related death in Europe and the USA by 2030. With a 5-year overall survival rate of less than 10% the prognosis remains poor. So far surgical tumor resection remains the only curative treatment option, which is now partially supported by multimodal neoadjuvant and adjuvant therapy concepts. Due to the aggressive tumor biology patients with advanced pancreatic cancer in particular can profit from these multimodal therapy concepts. Additionally, in recent years surgical treatment was optimized, the criteria for tumor resectablity were defined and minimally invasive surgery was widely introduced. This review article summarizes the newest developments and the new German S3 guidelines concerning surgery of pancreatic cancer.</p>","PeriodicalId":50700,"journal":{"name":"Chirurg","volume":"93 1","pages":"446-452"},"PeriodicalIF":0.0000,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"[Surgical treatment of pancreatic cancer-What is new?]\",\"authors\":\"Thomas Schmidt, Orlin Belyaev, Waldemar Uhl, Christiane J Bruns\",\"doi\":\"10.1007/s00104-022-01618-7\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The incidence of pancreatic ductal adenocarcinoma is continuously increasing and will become the second leading cause of cancer-related death in Europe and the USA by 2030. With a 5-year overall survival rate of less than 10% the prognosis remains poor. So far surgical tumor resection remains the only curative treatment option, which is now partially supported by multimodal neoadjuvant and adjuvant therapy concepts. Due to the aggressive tumor biology patients with advanced pancreatic cancer in particular can profit from these multimodal therapy concepts. Additionally, in recent years surgical treatment was optimized, the criteria for tumor resectablity were defined and minimally invasive surgery was widely introduced. This review article summarizes the newest developments and the new German S3 guidelines concerning surgery of pancreatic cancer.</p>\",\"PeriodicalId\":50700,\"journal\":{\"name\":\"Chirurg\",\"volume\":\"93 1\",\"pages\":\"446-452\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Chirurg\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00104-022-01618-7\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2022/3/31 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Chirurg","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00104-022-01618-7","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2022/3/31 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
[Surgical treatment of pancreatic cancer-What is new?]
The incidence of pancreatic ductal adenocarcinoma is continuously increasing and will become the second leading cause of cancer-related death in Europe and the USA by 2030. With a 5-year overall survival rate of less than 10% the prognosis remains poor. So far surgical tumor resection remains the only curative treatment option, which is now partially supported by multimodal neoadjuvant and adjuvant therapy concepts. Due to the aggressive tumor biology patients with advanced pancreatic cancer in particular can profit from these multimodal therapy concepts. Additionally, in recent years surgical treatment was optimized, the criteria for tumor resectablity were defined and minimally invasive surgery was widely introduced. This review article summarizes the newest developments and the new German S3 guidelines concerning surgery of pancreatic cancer.
期刊介绍：
Der Chirurg; Zeitschrift fur Alle Gebiete der Operativen Medizen
The magazine is intended for surgeons in hospitals, clinics and research.
Each issue includes a comprehensive theme: Practical summaries access to selected topics and provide the reader with a compilation of current knowledge in all fields of surgery. Besides imparting relevant background knowledge, the emphasis is on the review of scientific results and practical experience. The reader will find concrete recommendations.
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