抗癫痫药物的药代动力学监测

A. Aldaz , R. Ferriols , D. Aumente , M.V. Calvo , M.R. Farre , B. García , R. Marqués , P. Mas , B. Porta , M. Outeda , D. Soy , Grupo PK-gen de la Sociedad Española de Farmacia Hospitalaria
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引用次数: 5

摘要

监测用于治疗和预防癫痫的抗癫痫药物的血浆水平是通过减少不良影响和提高有效性来改善临床结果的策略之一。本文的目的是回顾抗癫痫药物监测的基本方面,使用由Sociedad Española de Farmacia Hospitalaria(西班牙医院药剂师协会)的药代动力学和药物遗传学工作组(pkgen)准备和认可的共识文件。
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Pharmacokinetic Monitoring of Antiepileptic Drugs

Monitoring plasma levels of antiepileptic drugs for the treatment and prophylaxis of epilepsy is one of the strategies enabling clinical results to improve by reducing adverse affects and increasing effectiveness.

The objective of this article is to review the basic aspects in the monitoring of antiepileptic drugs using a consensus document prepared and endorsed by the pharmacokinetics and pharmacogenetics working group (PK.gen) of the Sociedad Española de Farmacia Hospitalaria (Spanish Society of Hospital Pharmacists).

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