心血管死亡率和危险因素:波兰是否在重复美国30年前的经验?

Mark W. Massing , Stefan L. Rywik , Grazyna B. Broda , Bogdan Jasinski , Andrzej Pajak , Herman A. Tyroler , O. Dale Williams , Teri A. Manolio
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引用次数: 2

摘要

背景:在美国和波兰,心血管疾病(CVD)已成为导致死亡的主要原因。近几十年来,两国心血管疾病和冠心病(CHD)死亡率都发生了变化。我们检查了这两个国家的死亡率趋势,并考虑了它们与同期危险因素暴露变化的关系。方法死亡率和人口数据来自波兰主要统计局(1970 - 1996)、美国社区结构项目(1962-67)和美国国家卫生统计中心(1968-2000)。采用局部回归生成35-64岁年龄段的最佳拟合、年龄标准化死亡率趋势曲线,并采用分段对数线性回归进行量化。从已发表的资料和Pol-MONICA数据中获得同期风险因素暴露。结果美国的死亡率持平并下降,波兰的死亡率上升,导致波兰的死亡率超过美国高加索人,接近或超过非洲裔美国人。波兰死亡率上升的趋势在1991年发生逆转,此后呈下降趋势,特别是冠心病。美国死亡率的下降伴随着多种危险因素的减少。在波兰,冠心病发病率下降期间,风险因素暴露也有所减少,但与美国的经验有所不同。结论:20世纪90年代波兰心血管疾病死亡率上升趋势的逆转与30年前美国的类似逆转相似,并伴随着两国风险因素暴露的减少。比较两国经验的相似性表明,努力减少人口接触可预防危险因素的重要性。
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Cardiovascular mortality and risk factors: Is Poland repeating the US experience of 30 years ago?

Background

Cardiovascular diseases (CVD) have been leading causes of death in the United States (US) and Poland. CVD and coronary heart disease (CHD) death rates have changed in both countries in recent decades. We examined these mortality trends in the two countries and considered their relations to contemporaneous changes in risk factor exposures.

Methods

Mortality and population data were obtained from the Polish Main Statistical Office (1970–96), the US Community Structures Project (1962–67), and the US National Center for Health Statistics (1968–2000). Best-fit, age-standardized, mortality rate trend curves for ages 35–64 years were generated with local regression and were quantified with piecewise log-linear regression. Contemporaneous risk factor exposures were obtained from published sources and from Pol-MONICA data.

Results

While mortality rates leveled and declined in the US, they increased in Poland resulting in Polish rates exceeding those of US Caucasians and approaching or exceeding those of African Americans. Increasing mortality rate trends in Poland reversed in 1991, and declined thereafter, especially for CHD. US mortality declines were accompanied by reductions in multiple risk factors. Decreased risk factor exposures were noted during CHD declines in Poland, but differed somewhat from the US experience.

Conclusions

The reversal of increasing CVD mortality rate trends in Poland during the 1990s is reminiscent of a similar reversal in the US 30 years earlier and was accompanied by reduced risk factor exposures in both countries. The similarity of experiences comparing the two countries demonstrates the importance of efforts to reduce population exposures to preventable risk factors.

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