心脏结节病是无症状青年患者非常罕见的猝死原因

Francisco García-Molina , Francisco Martínez-Díaz , Juan Pedro Hernández del Rincón , Matias Martínez-Pérez , Francisco Pastor-Quirante
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引用次数: 0

摘要

结节病的心脏受累在有症状和无症状的患者中均有描述。本报告的目的是进一步了解结节病及其临床表现。我们报告了两例青年男性猝死的尸检和毒理学结果。一名37岁男性患有纵隔腺全身性结节病和左心室肌内肉芽肿病,导致心室壁增厚14mm,继发性扩张性心肌病导致猝死。一名27岁男性,肺部和纵隔广泛结节病。在心壁发现了具有纤维化背景的肉芽肿,这可能是导致猝死的心律失常机制的起源。尸检,包括仔细检查心脏传导通路,对于确定猝死原因至关重要。
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Sarcoidosis cardíaca como causa muy infrecuente de muerte súbita en pacientes jóvenes asintomáticos

Cardiac involvement in sarcoidosis has been described in both symptomatic and asymptomatic patients. The aim of this report is to further the understanding of sarcoidosis and its clinical presentation. We report the autopsy and toxicology results of two cases of sudden death in young men. A 37-year-old male had generalized sarcoidosis, in mediastinal glands and intramyocardial sarcoid granulomas in the left ventricle, which had caused a 14 mm thickening of the ventricular wall and a secondary dilated myocardiopathy causing sudden death. A 27-year-old male had extensive sarcoidosis of the lungs and mediastinum. Granulomas with a fibrotic background were found in the cardiac wall which could have originated an arrhythmogenic mechanism causing sudden death. Post-mortem study including careful examination of cardiac conduction pathways are vital to ascertain the cause of sudden death.

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来源期刊
Revista Espanola de Patologia
Revista Espanola de Patologia Medicine-Pathology and Forensic Medicine
CiteScore
0.90
自引率
0.00%
发文量
53
审稿时长
34 days
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