骨质疏松症药物的消费者、处方和处方者

Ignacia Idarreta , Eva Rua , Francisco Javier Hernando , Koro Zabaleta , María Jesús Arzuaga , María Isabel Irizar
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引用次数: 2

摘要

目的了解骨质疏松药物处方者和消费者的特点。DesignCross-sectional研究。为西吉普斯科阿县(西班牙)设立了34个初级保健区。参与者年龄大于13岁,随机从服用骨质疏松药物1年的1673人中选取。干预:通过临床访谈和病历数据完成的问卷。主要测量指标危险因素、药物、骨密度(BMD)、处方、骨折风险。结果512人(90.6%为女性),平均年龄68.9岁,服用骨质疏松药物898种。50岁前有骨折史的占24.6%,生育未满30年的占21.5%。骨密度为50.4%;其中52.8%为骨质疏松症。三分之一的骨密度扫描不合理。使用最广泛的药物是钙,含或不含维生素D(53.4%),其次是双膦酸盐(33.95%)。处方由风湿病医生(29.2%)、创伤医生、妇科医生和初级保健医生(12.4%)开具。三分之一(30.6%)没有基于最佳证据。根据Black评分,骨折高危患者为23.8±3.9%(37.8%为初级保健,0%为妇科)。结论骨质疏松药物在骨密度、危险因素或骨折风险不允许的情况下使用。专科医生开出的这些药和初级保健医生开的一样多,甚至更多。为合理管理该病制定标准化标准势在必行。
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Consumidores, prescripción y prescriptores de fármacos para la osteoporosis

Objective

To determine the characteristics of prescribers and consumers of osteoporosis drugs.

Design

Cross-sectional study.

Setting

34 primary care areas for the county of West Gipuzkoa (Spain).

Participants

People older than 13 years, randomly selected from 1673 persons consuming osteoporosis drugs for 1 year.

Intervention

A questionnaire completed through clinical interview and data from the medical record.

Main measurements

Risk factors, drugs, bone mineral density (BMD), prescribers, fracture risk.

Results

We studied 512 persons (90.6% women), with a mean age of 68.9 years, taking 898 drugs for osteoporosis. A total of 24.6% had a history of fracture before the age of 50 years and 21.5% of women were fertile for less than 30 years. BMD was available in 50.4%; of these, 52.8% were osteoporotic. One in three BMD scans performed were not justified. The most widely prescribed drug was calcium, with or without vitamin D (53.4%), followed by biphosphonates (33.95%). Prescriptions were issued by rheumatologists (29.2%), traumatologists, gynecologists and primary care physicians (12.4%). One-third (30.6%) were not based on the best evidence. According to the Black scale, 23.8 ± 3.9% had a high risk of fracture (37.8% primary care, 0% gynecology).

Conclusions

Osteoporosis drugs are being used when not warranted by BMD, risk factors or fracture risk. Specialists prescribe these drugs as much or more than primary care physicians. Standardization of criteria for the rational management of this disease is imperative.

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Gaceta Medica de Bilbao
Gaceta Medica de Bilbao Medicine-Medicine (all)
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