特发性肥厚性颅厚膜炎:病例报告

Q4 Medicine Gaceta Medica de Bilbao Pub Date : 2010-07-01 DOI:10.1016/S0304-4858(10)70025-1

Patricia Quintero-Cusguen , Ángela M. Gutiérrez-Álvarez , Iván M. Herrera-Rojas

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摘要

颅特发性肥厚性脑膜炎是一种罕见的疾病，其特征是慢性炎症导致硬脑膜增厚。头痛、多发性颅神经病变和磁共振显示gd - dtpa增强硬脑膜增厚有助于诊断。我们报告一个69岁的男性尸检病例慢性头痛和视力丧失由于视神经损伤发展超过3个月，谁被诊断为肥厚性厚性脑膜炎。脑脊液有炎性改变。硬脑膜增厚的样本显示慢性肉芽肿性炎症，没有血管炎或感染或肿瘤过程的迹象。特发性肥厚性厚性脑膜炎是一种排除性诊断。详尽的检查(细菌学和组织病理学)，以确定原因硬脑膜增厚在我们的病人证明是不成功的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Paquimeningitis craneal hipertrófica idiopática: reporte de caso

Cranial idiopathic hypertrophic pachymeningitis is a rare disorder characterized by chronic inflammation causing thickening of the dura mater. Headache, multiple cranial neuropathy and magnetic resonance images showing GD-DTPA-enhanced thickened dura can aid diagnosis.

We report the autopsy case of a 69-year-old man with chronic headache and visual loss due to optic nerve damage developing over a 3-month period, who was diagnosed with hypertrophic pachymeningitis. Cerebrospinal fluid showed inflammatory changes. The sample of hypertrophied dura mater revealed chronic granulomatous inflammation without signs of vasculitis or infectious or neoplastic processes.

Idiopathic hypertrophic pachymeningitis is an exclusion diagnosis. Exhaustive tests (both bacteriological and histopathological) to identify the cause of dural thickening in our patient proved unsuccessful.

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