胎儿酒精谱系障碍的神经精神影响和长期后果

A. Streissguth, K. O’Malley
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引用次数: 446

摘要

产前酒精暴露可导致中枢神经系统(CNS)的整个频谱的后遗症,持续整个生命周期,并表现为一系列的影响,从临床难以区分到严重损害。酒精作为致畸物的最大影响是对大脑——最需要的是对相关精神障碍的整体治疗和管理。这种细微的脑损伤与酗酒母亲生下孩子所产生的复杂社会心理环境相互作用,可能进一步影响发育,并导致代价高昂和毁灭性的社会后果。目前迫切需要对这些细微的大脑先天缺陷的慢性神经精神后遗症进行研究。识别这些胎儿酒精谱系障碍(FASD)在精神病学术语是必要的一步,以集中注意力和资源的精神卫生领域对这一个人和社会的重大问题。
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Neuropsychiatric implications and long-term consequences of fetal alcohol spectrum disorders.
Prenatal alcohol exposure can cause a whole spectrum of central nervous system (CNS) sequelae that persist throughout the life span and manifest in a spectrum of effects from clinically indistinguishable to severely impairing. The greatest impact of alcohol as a teratogen is to the brain-the greatest need is for holistic treatment and management of the associated mental disorders. The interaction of this subtle brain damage with the complex psychosocial circumstances surrounding the birth of a child to a mother with alcohol problems can further compound development and result in costly and devastating social consequences. Research is urgently needed on the chronic neuropsychiatric sequelae of these subtle birth defects of the brain. Identification of these fetal alcohol spectrum disorders (FASD) in the psychiatric nomenclature is a necessary step to focus the attention and resources of the mental health field on this personally and socially significant problem.
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