无症状细菌性尿症肾病患者不需要治疗:一项试点观察性审计的结果

Leyland Chuang MBBS, MRCP , Norshima Nashi , Anantharaman Vathsala MD, FRCP, FAMS , Paul Ananth Tambyah MBBS, MD
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引用次数: 0

摘要

无症状细菌性尿的治疗仍然是不适当使用抗生素的常见原因,特别是在患有多种合并症(如肾脏疾病)的患者中。方法对200例肾脏患者进行前瞻性、回顾性、观察性审计,以评估无症状性细菌尿(未给予抗生素治疗)患者与有症状性尿路感染患者再入院率和死亡率的显著差异。结果细菌尿19例(9.5%),其中有症状尿路感染12例,无症状尿路感染7例。无症状性菌尿患者均未接受有效抗生素治疗。与有症状的尿路感染患者相比,未经治疗的无症状菌尿患者的再入院率(42.9% vs . 33.3%;P = 1.00)或死亡率(0% vs . 8.3%;P = 1.00)无差异。结论本初步研究提示无症状性细菌性尿症患者不进行治疗是安全的。
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Renal patients with asymptomatic bacteriuria do not need to be treated: results of a pilot observational audit

Introduction

Treatment of asymptomatic bacteriuria remains a common cause of inappropriate antibiotic use, particularly among patients with multiple comorbidities such as renal disease.

Methods

A pilot, retrospective, observational audit of 200 renal patients was conducted to evaluate significant differences in readmission and mortality rates between patients with asymptomatic bacteriuria (who were not given antibiotic treatment) and patients with symptomatic urinary tract infections.

Results

Nineteen (9.5%) patients had bacteriuria: 12 with symptomatic urinary tract infection and 7 with asymptomatic bacteriuria. None of the patients with asymptomatic bacteriuria were treated with effective antibiotics. There was no difference in readmission (42.9% v. 33.3%;P = 1.00) or mortality rates (0% v. 8.3%;P = 1.00) for patients with untreated asymptomatic bacteriuria when compared with patients with symptomatic urinary tract infections.

Conclusions

This pilot study suggests that it is safe not to treat asymptomatic bacteriuria in renal patients.

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