Kazushige Seki, T. Kanchiku, A. Tokushige, H. Ogasa, T. Imagama, T. Seki, T. Taguchi
{"title":"类风湿关节炎晨僵:用功率多普勒超声和综合评分评估其与疾病活动度的关系","authors":"Kazushige Seki, T. Kanchiku, A. Tokushige, H. Ogasa, T. Imagama, T. Seki, T. Taguchi","doi":"10.1080/24708593.2017.1365797","DOIUrl":null,"url":null,"abstract":"Abstract Objective: This study investigated potential associations of morning stiffness (MS) with rheumatoid arthritis (RA) disease activity and ultrasonography (US). Methods: We conducted a cross-sectional analysis of 100 consecutive patients with RA divided into MS-positive group (n = 38) and MS-negative group (n = 62). US findings, disease activity score in 28 joints (DAS28) and Clinical Disease Activity Index (CDAI) were compared. Results: DAS28, CDAI and the number of power Doppler (PD) signal-positive joints were significantly higher in the MS-positive group (p < 0.01). The number of patients who did not achieve the DAS28 or CDAI remission criteria was significantly higher in the MS-positive group (p < 0.01). When cut-off points were applied, MS duration of ≥10 min was associated with PD signal-positive joints, with a sensitivity of 47.5% and a specificity of 92.3% (area under curve = 0.7087, chi-square test: p < 0.0001). Conclusion: This study showed that in patients with MS duration of ≥10 min, there was a high probability of PD-positive joints in the hand.","PeriodicalId":91773,"journal":{"name":"Myopain","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2015-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/24708593.2017.1365797","citationCount":"1","resultStr":"{\"title\":\"Morning Stiffness in Rheumatoid Arthritis: Investigating its Relationship with Disease Activity as Assessed by Power Doppler Ultrasonography and Composite Scores\",\"authors\":\"Kazushige Seki, T. Kanchiku, A. Tokushige, H. Ogasa, T. Imagama, T. Seki, T. Taguchi\",\"doi\":\"10.1080/24708593.2017.1365797\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Abstract Objective: This study investigated potential associations of morning stiffness (MS) with rheumatoid arthritis (RA) disease activity and ultrasonography (US). Methods: We conducted a cross-sectional analysis of 100 consecutive patients with RA divided into MS-positive group (n = 38) and MS-negative group (n = 62). US findings, disease activity score in 28 joints (DAS28) and Clinical Disease Activity Index (CDAI) were compared. Results: DAS28, CDAI and the number of power Doppler (PD) signal-positive joints were significantly higher in the MS-positive group (p < 0.01). The number of patients who did not achieve the DAS28 or CDAI remission criteria was significantly higher in the MS-positive group (p < 0.01). When cut-off points were applied, MS duration of ≥10 min was associated with PD signal-positive joints, with a sensitivity of 47.5% and a specificity of 92.3% (area under curve = 0.7087, chi-square test: p < 0.0001). Conclusion: This study showed that in patients with MS duration of ≥10 min, there was a high probability of PD-positive joints in the hand.\",\"PeriodicalId\":91773,\"journal\":{\"name\":\"Myopain\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2015-10-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1080/24708593.2017.1365797\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Myopain\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/24708593.2017.1365797\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Myopain","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/24708593.2017.1365797","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Morning Stiffness in Rheumatoid Arthritis: Investigating its Relationship with Disease Activity as Assessed by Power Doppler Ultrasonography and Composite Scores
Abstract Objective: This study investigated potential associations of morning stiffness (MS) with rheumatoid arthritis (RA) disease activity and ultrasonography (US). Methods: We conducted a cross-sectional analysis of 100 consecutive patients with RA divided into MS-positive group (n = 38) and MS-negative group (n = 62). US findings, disease activity score in 28 joints (DAS28) and Clinical Disease Activity Index (CDAI) were compared. Results: DAS28, CDAI and the number of power Doppler (PD) signal-positive joints were significantly higher in the MS-positive group (p < 0.01). The number of patients who did not achieve the DAS28 or CDAI remission criteria was significantly higher in the MS-positive group (p < 0.01). When cut-off points were applied, MS duration of ≥10 min was associated with PD signal-positive joints, with a sensitivity of 47.5% and a specificity of 92.3% (area under curve = 0.7087, chi-square test: p < 0.0001). Conclusion: This study showed that in patients with MS duration of ≥10 min, there was a high probability of PD-positive joints in the hand.