Fei-Long Yu, Huan Miao, Jinjin Xia, Fan Jia, Huadong Wang, Fuqiang Xu, Lin Guo
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Front Cover: Proteomics Analysis Identifies IRSp53 and Fascin as Critical for PRV Egress and Direct Cell–Cell Transmission
DOI: 10.1002/pmic.201900009
In article number 1900009, Fei-Long Yu et al. provide a comprehensive proteomics analysis of mature extracellular and intracellular Pseudorabies virus (PRV) virions based on a virion purification strategy. PRV virions are isolated from infected culture cells through a flow cytometry sorting-based method, and the extracellular and intracellular PRV proteomes are characterized and compared. The cover depicts a dual fluorescent image showing Pseudorabies viruses (PRV) with tags on the envelope glycoprotein M-GFP and the capsid protein VP26-RFP.
期刊介绍：
PROTEOMICS is the premier international source for information on all aspects of applications and technologies, including software, in proteomics and other "omics". The journal includes but is not limited to proteomics, genomics, transcriptomics, metabolomics and lipidomics, and systems biology approaches. Papers describing novel applications of proteomics and integration of multi-omics data and approaches are especially welcome.
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