仰卧位与俯卧位胆道碎石的疗效:一项体外研究。

B. R. Baumgartner, J. H. Goldstein, W. Torres
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摘要

临床体外冲击波碎石(ESWL)结果显示,体外冲击波碎石后的胆囊结石碎片越小,患者的结石清除速度越快。在ESWL中,尝试产生沙状碎片,使其易于通过胆囊和胆总管。从胆囊切除术标本中取出16对形状、大小和组成相同的胆结石,然后分别在多尼尔MPL-9000碎石机(多尼尔医疗系统公司)上碎石机粉碎,以模拟患者仰卧位或俯卧位。在仰卧位和俯卧位治疗后比较剩余碎片的数量和大小。32颗直径从5-15毫米不等的宝石在21千伏的电压下接受了1500次冲击波。在750和1500冲击波后,测量和计数了最大直径大于或等于4mm的碎片。16例仰卧位结石中有4例(25%)碎片大于或等于4毫米,16例俯卧位结石中有16例(100%)碎片大于或等于4毫米。16例中有14例(88%)的易发组出现了最大的残余碎片,无论每对结石的大小如何。在该体外模型中,仰卧位胆道碎石术能更有效地粉碎胆结石;这些发现表明,患者仰卧位可以改善碎片化和治疗成功率。
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Efficacy of supine versus prone biliary lithotripsy: an in vitro study.
Clinical extracorporeal shock wave lithotripsy (ESWL) results have shown that the smaller the gallstone fragments following ESWL, the faster the patient will become stone-free. At ESWL, an attempt is made to produce sand-like fragments that will easily pass through the cystic and common bile ducts. Sixteen pairs of gallstones of equal shape, size, and composition were harvested from cholecystectomy specimens and then fragmented on the Dornier MPL-9000 lithotripter (Dornier Medical Systems, Inc.), individually, in a phantom oriented to duplicate either supine or prone patient positions. The number and size of remaining fragments were compared following the supine versus prone treatments. The 32 stones, ranging from 5-15 mm in diameter, received 1,500 shock waves at 21 kV. Fragments with a maximal diameter of greater than or equal to 4 mm were measured and counted after 750 and 1,500 shock waves. Fragments greater than or equal to 4 mm were found in four out of 16 stones treated supine (25%) and 16 out of 16 stones treated prone (100%). The largest residual fragment regardless of size for each stone pair occurred in the prone group in 14 out of 16 cases (88%). Biliary lithotripsy performed with supine positioning results in more efficacious gallstone fragmentation in this in vitro model; these findings suggest that supine positioning for patients could improve fragmentation and treatment success.
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Improved results of extracorporeal shock wave lithotripsy with the Dornier MPL 9000 for single gallstones. Inhibitory effect of high energy shock waves and radiotherapy in vitro. The influence of electrode shape on the performance of electrohydraulic lithotripters. Evaluation of patient controlled sedation and analgesia for ESWL. Treatment of ureteral calculi with an 8.3F disposable shaft rigid ureteroscope.
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