{"title":"合成生物系统设计自动化","authors":"D. Densmore, S. Hassoun","doi":"10.1109/MDT.2012.2193370","DOIUrl":null,"url":null,"abstract":"Through principled engineering methods, synthetic biology aims to build specialized biological components that can be modularly composed to create complex systems. This article outlines bio-design automation using two complementary design approaches, bottom-up modular construction from biological primitives and pathway-based approaches. The article also highlights future challenges for both.","PeriodicalId":50392,"journal":{"name":"IEEE Design & Test of Computers","volume":"29 1","pages":"7-20"},"PeriodicalIF":0.0000,"publicationDate":"2012-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/MDT.2012.2193370","citationCount":"23","resultStr":"{\"title\":\"Design Automation for Synthetic Biological Systems\",\"authors\":\"D. Densmore, S. Hassoun\",\"doi\":\"10.1109/MDT.2012.2193370\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Through principled engineering methods, synthetic biology aims to build specialized biological components that can be modularly composed to create complex systems. This article outlines bio-design automation using two complementary design approaches, bottom-up modular construction from biological primitives and pathway-based approaches. The article also highlights future challenges for both.\",\"PeriodicalId\":50392,\"journal\":{\"name\":\"IEEE Design & Test of Computers\",\"volume\":\"29 1\",\"pages\":\"7-20\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2012-04-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1109/MDT.2012.2193370\",\"citationCount\":\"23\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IEEE Design & Test of Computers\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1109/MDT.2012.2193370\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IEEE Design & Test of Computers","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/MDT.2012.2193370","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Design Automation for Synthetic Biological Systems
Through principled engineering methods, synthetic biology aims to build specialized biological components that can be modularly composed to create complex systems. This article outlines bio-design automation using two complementary design approaches, bottom-up modular construction from biological primitives and pathway-based approaches. The article also highlights future challenges for both.