使用“低剂量”霉酚酸酯减少肾移植后患者急性排斥反应的新策略

Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO) Pub Date : 1999-06-01 DOI:10.1177/090591999900900209

P. Ulsh, Harold C. Yang, M. Holman, N. Ahsan

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摘要

移植协调杂志，第9卷，第2期，1999年6月，环孢素为基础的方案，急性排斥发作超过50%在一些中心。几位作者已经证明，这些急性排斥反应的频率和严重程度显著缩短了同种异体肾移植的总体半衰期。根据这一观察结果，最近的许多研究都使用急性排斥反应的数量和严重程度作为主要疗效终点。使用“低剂量”霉酚酸酯减少肾移植后患者急性排斥反应的新策略

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New Strategies Using ‘Low-Dose’ Mycophenolate Mofetil to Reduce Acute Rejection in Patients following Kidney Transplantation

Journal of Transplant Coordination, Vol. 9, Number 2, June 1999 cyclosporine-based regimens, episodes of acute rejection exceed 50% in some centers. Several authors have demonstrated that the frequency and severity of these acute rejections significantly shorten the overall halflife of renal allografts.2,3 With this observation, many of the recent studies have used the number and severity of acute rejections as primary efficacy end point. New strategies using ‘low-dose’ mycophenolate mofetil to reduce acute rejection in patients following kidney transplantation

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Journal of transplant coordination : official publication of the North American Transplant Coordinators Organization (NATCO)

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