Research Progress of Blood Indexes in Differentiating the Severity of Acute Appendicitis in Children

Appendicitis is one of the most common abdominal surgical emergencies in children. Accurate diagnosis of appendicitis in children remains challenging in many cases. Acute appendicitis was divided into acute uncomplicated appendicitis (UA) and complicated appendicitis (CA) according to the intraoperative condition and postoperative histopathological classification. Appendectomy has always been the gold standard for AA treatment, but current studies have shown that conservative treatment in some children with UA has a good effect, so it is necessary to distinguish different severity of appendicitis before surgery. This study explores its application in differentiating the severity of acute appendicitis based on blood indicators. The results show that: CRP, PCT, SAA, FIB, PLT, PLR, DD, PT, serum sodium, serum total bilirubin, and some new Indicators such as DLAC, PTX3, FA, DNI are meaningful in diagnosing CA