{"title":"克非兰饲喂对大鼠粪便胆固醇排泄、肝损伤及肠道组胺浓度的影响","authors":"H. Maeda, H. Mizumoto, Makoto Suzuki, K. Tsuji","doi":"10.12938/BIFIDUS.24.35","DOIUrl":null,"url":null,"abstract":"The natural polysaccharide, kefiran (galactoglucan), was studied for the mechanism of its serum cholesterol lowering effect in 2 rat models one, loaded with cholesterol and another given erotic acid. Kefiran accelerated sterol excretion and protected hepatic injuries (GOT, GPT) in both models. In addition, histamine excretion decreased in the cecum content and feces, suggesting that kefiran may have various preventative functions.","PeriodicalId":90114,"journal":{"name":"Bioscience and microflora","volume":"24 1","pages":"35-40"},"PeriodicalIF":0.0000,"publicationDate":"2005-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.12938/BIFIDUS.24.35","citationCount":"16","resultStr":"{\"title\":\"Effects of Kefiran-Feeding on Fecal Cholesterol Excretion, Hepatic Injury and Intestinal Histamine Concentration in Rats\",\"authors\":\"H. Maeda, H. Mizumoto, Makoto Suzuki, K. Tsuji\",\"doi\":\"10.12938/BIFIDUS.24.35\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The natural polysaccharide, kefiran (galactoglucan), was studied for the mechanism of its serum cholesterol lowering effect in 2 rat models one, loaded with cholesterol and another given erotic acid. Kefiran accelerated sterol excretion and protected hepatic injuries (GOT, GPT) in both models. In addition, histamine excretion decreased in the cecum content and feces, suggesting that kefiran may have various preventative functions.\",\"PeriodicalId\":90114,\"journal\":{\"name\":\"Bioscience and microflora\",\"volume\":\"24 1\",\"pages\":\"35-40\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2005-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.12938/BIFIDUS.24.35\",\"citationCount\":\"16\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bioscience and microflora\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.12938/BIFIDUS.24.35\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioscience and microflora","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.12938/BIFIDUS.24.35","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Effects of Kefiran-Feeding on Fecal Cholesterol Excretion, Hepatic Injury and Intestinal Histamine Concentration in Rats
The natural polysaccharide, kefiran (galactoglucan), was studied for the mechanism of its serum cholesterol lowering effect in 2 rat models one, loaded with cholesterol and another given erotic acid. Kefiran accelerated sterol excretion and protected hepatic injuries (GOT, GPT) in both models. In addition, histamine excretion decreased in the cecum content and feces, suggesting that kefiran may have various preventative functions.
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