{"title":"具有传播模式和分布延迟的离散病毒感染模型","authors":"B. E. Boukari, K. Hattaf, J. E. Ghordaf","doi":"10.1504/IJDSDE.2021.10036608","DOIUrl":null,"url":null,"abstract":": The aim of this work is to propose and analyse a discrete virus dynamics model with distributed delays and both modes of transmission, one by virus-to-cell infection and the other by cell-to-cell transfer. In the proposed model, the first distributed delays describes the time needed for infected cells to produce new virions, and the second portrays the time necessary for the newly produced virions to become mature and infectious. In addition, the infection transmission process is modelled by general incidence functions for both modes. Furthermore, we prove that the proposed discrete model has the same dynamics as the corresponding continuous model, such as positivity, boundedness and global behaviours of solutions with no restriction on the time step size. Moreover, numerical simulations are given to illustrate and confirm our main analytical results.","PeriodicalId":43101,"journal":{"name":"International Journal of Dynamical Systems and Differential Equations","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A discrete viral infection model with both modes of transmission and distributed delays\",\"authors\":\"B. E. Boukari, K. Hattaf, J. E. Ghordaf\",\"doi\":\"10.1504/IJDSDE.2021.10036608\",\"DOIUrl\":null,\"url\":null,\"abstract\":\": The aim of this work is to propose and analyse a discrete virus dynamics model with distributed delays and both modes of transmission, one by virus-to-cell infection and the other by cell-to-cell transfer. In the proposed model, the first distributed delays describes the time needed for infected cells to produce new virions, and the second portrays the time necessary for the newly produced virions to become mature and infectious. In addition, the infection transmission process is modelled by general incidence functions for both modes. Furthermore, we prove that the proposed discrete model has the same dynamics as the corresponding continuous model, such as positivity, boundedness and global behaviours of solutions with no restriction on the time step size. Moreover, numerical simulations are given to illustrate and confirm our main analytical results.\",\"PeriodicalId\":43101,\"journal\":{\"name\":\"International Journal of Dynamical Systems and Differential Equations\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2021-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Dynamical Systems and Differential Equations\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1504/IJDSDE.2021.10036608\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MATHEMATICS, APPLIED\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Dynamical Systems and Differential Equations","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1504/IJDSDE.2021.10036608","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MATHEMATICS, APPLIED","Score":null,"Total":0}
A discrete viral infection model with both modes of transmission and distributed delays
: The aim of this work is to propose and analyse a discrete virus dynamics model with distributed delays and both modes of transmission, one by virus-to-cell infection and the other by cell-to-cell transfer. In the proposed model, the first distributed delays describes the time needed for infected cells to produce new virions, and the second portrays the time necessary for the newly produced virions to become mature and infectious. In addition, the infection transmission process is modelled by general incidence functions for both modes. Furthermore, we prove that the proposed discrete model has the same dynamics as the corresponding continuous model, such as positivity, boundedness and global behaviours of solutions with no restriction on the time step size. Moreover, numerical simulations are given to illustrate and confirm our main analytical results.
期刊介绍:
IJDSDE is a quarterly international journal that publishes original research papers of high quality in all areas related to dynamical systems and differential equations and their applications in biology, economics, engineering, physics, and other related areas of science. Manuscripts concerned with the development and application innovative mathematical tools and methods from dynamical systems and differential equations, are encouraged.