冠脉压力试验作为慢性心力衰竭患者生活质量的预测指标

B. Taneva, Dejan Ristevski
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摘要

摘要介绍。运动耐量是慢性心力衰竭患者的生活质量指标之一。我们研究的目的是通过评估慢性心力衰竭患者的运动耐受性来评估他们的生活质量。方法。我们对113例稳定性慢性心力衰竭患者进行了为期18个月的研究。他们被分为两组,对照组(常规治疗血管紧张素转换酶抑制剂和利尿剂)和治疗组(常规治疗加-受体阻滞剂)。治疗组根据服用受体阻滞剂分为3个亚组(美托洛尔、比索洛尔、卡维地洛亚组)。每6个月通过冠状动脉运动负荷测试检测运动耐受性(仅在NYHA FC II和III患者中),6分钟布鲁斯试验后症状得到限制或改善。结果。我们的结果显示,对照组与各治疗亚组在NYHA FC、NYHA评分和研究结束时的运动耐量方面有统计学差异,但亚组间无差异。结论。-受体阻滞剂可以改善运动耐受性,这是决定生活质量的一个变量。
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Coronary Stress Test as a Predictor of Quality of Life in Chronic Heart Failure Patients
Abstract Introduction. Exercise tolerance is one of the life quality parmeters in chronic heart failure patients. The aim of our study was to assess the quality of life of patients with chronic heart failure by estimating their exercise tolerance. Methods. We examined 113 patients with stable chronic heart failure in the period of 18 months. They were divided in two groups, a control group (on conventional therapy of angiotensin-converting enzyme inhibitors and diuretics) and a therapy group (conventional therapy plus beta-blockers). The therapy group was divided into 3 subgroups according to the beta-blocker taken (a Metoprolol Bisoprolol and Carvedilol subgroup). Exercise tolerance was detected by coronary trade-mill stress testing every 6 months (only in patients of NYHA FC II and III), symptoms limited or modified after 6-minutes Bruce test. Results. Our results showed that there was a statistically significant difference between the control group and all the therapy subgroups in NYHA FC, NYHA score and exercise tolerance at the end of the study, but there was no difference among the subgroups. Conclusion. Beta-blockers improve the exercise tolerance as a variable defining quality of life.
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