Alina Y. Babenko, A. E. Neymark, K. Anisimova, Elena Nikolaevna
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Effects of bariatric surgery on the level of hormones that regulate body weight. What is the basis of success
The growth of obesity and type 2 diabetes incidence has made bariatric surgery a widespread method of treatment. The effectiveness of bariatric operations in the treatment of obesity and related metabolic diseases is thoroughly highlighted in medical literature. However, the results of surgery do not always correlate with type of operation. As before, the mechanisms have not been fully studied of how the bariatric surgery influence on insulinresistance, entero-insulin axes, adipokines. Understanding such mechanisms will allow us to determine more precisely the indications relating to surgical treatment, and enhance the effectiveness of surgery in specific patient. The review is focusing on the influence of various types of bariatric surgery on the level of adipokines and incretines that participate in regulation of appetite and of fat and carbohydrate metabolism. The article elaborates modern concepts related to the impact of bariatric operations on metabolic disorders in obesity.
期刊介绍：
Journal "Obesity and Metabolism" is a multidisciplinary forum for clinical and applied research in the field of biochemistry, physiology, pathophysiology, genetics, nutrition, as well as molecular, metabolic, psychological and epidemiological aspects of obesity and metabolism. The main subject "Metabolism" reviewed in the journal, includes fat, carbohydrate, protein, bone, fluid and electrolyte and other types of metabolism in the spectrum of pathology of the endocrine system. The priority direction of Journal "Obesity and Metabolism" is publishing modern high-quality original research on the effectiveness of new and existing treatments in any aspect of metabolic and endocrine diseases. Pre-clinical pharmacology, pharmacokinetics studies, meta-analyzes, addressed to drug safety and tolerance are also welcome for publication in the journal "Obesity and metabolism." Journal "Obesity and Metabolism" announces review articles that are balanced, clear and offer the reader a modern and critical analysis of the literature on the subject of the magazine. Case reports, and lecture materials are also published for highlighting for practitioners new approaches to diagnosis and treatment of patients with metabolic disorders and obesity.
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