单关节炎揭示克罗恩病中英夫利昔单抗诱导的系统性红斑狼疮

MOJ orthopedics & rheumatology Pub Date : 2019-01-01 DOI:10.15406/mojor.2019.11.00495

S. Bouomrani, F. Rekik, Ali Naffati, W. Mahdhaoui, A. Hammami, Dhia Eddine Amri

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摘要

英夫利昔单抗是一种嵌合单克隆抗体，是一种抗肿瘤坏死因子α (anti-TNFα)，越来越多地用于治疗严重和耐药形式的炎症性肠病(克罗恩病(CD)和溃疡性结肠炎(UC))。它的特点是效率高，耐受性好诱导性系统性红斑狼疮(SLE)仍然是这种生物治疗的一种特殊但潜在的严重并发症

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Monoarthritis revealing Infliximab-induced systemic lupus erythematosus in Crohn's disease

Infliximab, a chimeric monoclonal antibody, is an anti-tumor necrosis factor alpha (anti-TNFα) that is increasingly used for the treatment of severe and resistant forms of inflammatory bowel disease (Crohn’s disease (CD) and ulcerative colitis (UC)).1,2 It is characterized by its efficiency and good tolerance.2 Induced systemic lupus erythematosus (SLE) remains an exceptional but potentially serious complication of this biological treatment.1,2

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MOJ orthopedics & rheumatology

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