不同途径人体微塑料暴露及其对靶器官的潜在健康风险综述

IF 6.4 2区 环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES Current Pollution Reports Pub Date : 2023-08-17 DOI:10.1007/s40726-023-00273-8
Ziye Yang, Meixue Wang, Zhihong Feng, Ziqi Wang, Mingxia Lv, Jinghao Chang, Liqun Chen, Can Wang
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引用次数: 0

摘要

环境中的微塑料通过饮食、饮用水和吸入空气进入人体。在几种人体组织中广泛检测到微塑料。然而,关于人类可以摄入的微塑料数量以及对各种器官的潜在不利影响的知识有限。为了解决这些问题,我们回顾了通过不同途径摄入微塑料的类型和丰度,并总结了人类年平均摄入量。3名成人通过膳食途径(包括盐(5.00-7.00)× 103,鱼(0.50-1.20)×104,水果(4.48-4.62)× 105,蔬菜(2.96-9.55)×104)摄入微塑料约(4.88-5.77)× 105 /年。通过饮用水途径摄入的微塑料量约为(0.22-1.2)×106微塑料/年。大气环境对微塑料的吸入量接近(0.21-2.51)× 106微塑料/年[包括室内(0.16-2.30)× 106微塑料/年和室外(0.46-2.10)×105]。综上所述,我们发现人体通过吸入摄入微塑料最多,其次是饮用水和饮食。我们还总结了微塑料进入人体后在不同器官中富集的类型和丰度。进入体内的微塑料会越过屏障进入目标效应器官,对健康造成不良影响,主要包括诱导细胞内氧化应激、遗传毒性、生殖毒性和炎症反应。总之,接触微塑料会对生物体的健康造成许多不利影响。因此,需要提高对危机的认识,紧急讨论和实际行动,以减轻环境中的微塑料污染物。图形抽象
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Human Microplastics Exposure and Potential Health Risks to Target Organs by Different Routes: A Review

Purpose of Review

Microplastics in the environment enter the human body through diet, drinking water, and air inhalation. The widespread detection of microplastics in several human tissues was conducted. However, limited knowledge exists on the number of microplastics that can be ingested by humans and the potential adverse effects on various organs. To address these issues, we reviewed the types and abundance of microplastics through different pathways and summarized the average annual intake in humans.

Recent Findings

An adult can ingest about (4.88–5.77) × 105 microplastics/year through the dietary route [including salt (5.00–7.00) × 103, fish (0.50–1.20)×104, fruits (4.48–4.62) × 105, and vegetables (2.96–9.55)×104]. The amount of microplastics ingested via drinking water route was approximately (0.22–1.2)×106 microplastics/year. Inhalation of microplastics via atmospheric environment was nearly (0.21–2.51) × 106 microplastics/year [including indoor (0.16–2.30) × 106 and outdoor (0.46–2.10)×105].

Summary

In conclusion, we found that the human body ingests microplastics most through inhalation, followed by drinking water and diet. We also summarized the types and abundance of microplastics that were enriched in different organs after microplastics entered the human body. Microplastics entering the body would cross the barrier into the target effector organs and cause adverse health effects, mainly including induction of intracellular oxidative stress, genotoxicity, reproductive toxicity, and inflammatory responses. In conclusion, exposure to microplastics can cause many adverse effects on the health of the organism. Thus, an increased awareness of the crisis, urgent discussion, and practical actions are needed to mitigate microplastics contaminants in the environment.

Graphical Abstract

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来源期刊
Current Pollution Reports
Current Pollution Reports Environmental Science-Water Science and Technology
CiteScore
12.10
自引率
1.40%
发文量
31
期刊介绍: Current Pollution Reports provides in-depth review articles contributed by international experts on the most significant developments in the field of environmental pollution.By presenting clear, insightful, balanced reviews that emphasize recently published papers of major importance, the journal elucidates current and emerging approaches to identification, characterization, treatment, management of pollutants and much more.
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