手术对巴西南部有症状的肿瘤性脊髓压迫患者的活动状态的影响

Q4 Medicine Coluna/ Columna Pub Date : 2022-01-01 DOI:10.1590/s1808-185120222103263573
Guilherme Gago da Silva, J. Britz, Otávio Garcia Martins, N. Ferreira, M. Ferreira, P. Worm
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引用次数: 1

摘要

背景:脊髓压迫是脊柱转移和多发性骨髓瘤的常见并发症。大约30%的癌症患者在发病期间出现有症状的脊柱转移。及时诊断和手术治疗这些病变,虽然姑息治疗,有可能减少发病率和改善生活质量,通过改善运动功能。研究设计:对医疗记录进行回顾性分析。目的:评价巴西南部两个神经外科中心肿瘤脊髓压迫的术后功能恢复和流行病学特征。方法:我们回顾性分析了2003年1月至2021年7月在两个神经外科中心接受姑息性手术治疗转移性肿瘤症状性脊柱病变的所有患者的数据。分析患者的年龄、性别、神经系统状况、组织学类型、受累节段、并发症及住院时间。结果:共纳入82例患者。病变发生在胸椎60例。入院时,95%的患者有神经功能缺损,其中大部分为Frankel C(37%)。在组织病理学分析中,乳腺癌是最常见的原发部位。术后按Frankel评分法对46例(56%)患者的神经功能状况进行重新分类。其中22例(47%)恢复了行走能力。结论:转移性脊髓压迫的手术治疗改善了我们样本的神经状态和行走能力。证据等级II;回顾性研究。
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IMPACT OF SURGERY ON AMBULATORY STATUS IN PATIENTS WITH SYMPTOMATIC NEOPLASTIC SPINAL CORD COMPRESSION IN SOUTHERN BRAZIL
ABSTRACT Background: Spinal cord compression is a common complication of spine metastasis and multiple myeloma. About 30% of patients with cancer develop symptomatic spinal metastases during their illness. Prompt diagnosis and surgical treatment of these lesions, although palliative, are likely to reduce the morbidity and improve quality of life by improving ambulatory function. Study Design: Retrospective review of medical records. Objective: To evaluate postoperative functional recovery and the epidemiological profile of neoplastic spinal cord compression in two neurosurgical centers in southern Brazil. Methods: We retrospectively analyzed the data of all patients who underwent palliative surgery for symptomatic neoplastic spine lesion from metastatic cancer, in two neurosurgical centers, between January 2003 and July 2021. The variables age, sex, neurological status, histological type, affected segment, complications and length of hospitalization were analyzed. Results: A total of 82 patients were included. The lesions occurred in the thoracic spine in 60 cases. At admission, 95% of the patients had neurological deficits, most of which were Frankel C (37%). At histopathological analysis, breast cancer was the most common primary site. After surgery, the neurological status of 46 patients (56%) was reclassified according to the Frankel scale. Of these, 22 (47%) regained ambulatory capacity. Conclusion: Surgical treatment of metastatic spinal cord compression improved neurological status and ambulatory ability in our sample. Level of evidence II; Retrospective study.
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来源期刊
Coluna/ Columna
Coluna/ Columna Medicine-Surgery
CiteScore
0.40
自引率
0.00%
发文量
32
审稿时长
10 weeks
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