赖诺普利转苯那普利患者血压及不良反应的评价

W. Cantrell
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引用次数: 1

摘要

目的:比较稳定患者从赖诺普利转为等量贝那普利前后的血压、血清肌酐和血清钾。设计:回顾性分析1年期间的计算机医疗和药房记录,获取患者在服用赖诺普利期间和改用苯那普利后最后一次测量的血压、血清肌酐和血清钾。为了减少血管紧张素转换酶(ACE)抑制剂以外的其他因素的影响,排除了某些测量值。地点:位于美国西部的退伍军人事务医疗中心。患者:687例患者进行血压评估;血清肌酐433;血清钾422。患者以老年男性为主。主要观察指标:血压、血清钾、血清肌酐测定。结果:两组患者的收缩压、舒张压、血压差异无统计学意义。
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Evaluation of Blood Pressure and Adverse Effects in Patients Converted from Lisinopril to Benazepril
OBJECTIVE: To compare blood pressure, serum creatinine, and serum potassium in stable patients before and after conversion from lisinopril to an equivalent dose of benazepril. DESIGN: A retrospective analysis of computer medical and pharmacy records during a one-year period, to obtain the last measured blood pressure, serum creatinine, and serum potassium obtained while patients were receiving lisinopril and again after conversion to benazepril. Certain measurements were excluded to decrease the influence of factors others than the angiotensin converting enzyme (ACE) inhibitors. SETTING: A Veterans Affairs Medical Center located in the western United States. PATIENTS: 687 patients were evaluated for blood pressure; 433 for serum creatinine; and 422 for serum potassium. The patients were predominantly elderly males. MAIN OUTCOME MEASURES: Measures of blood pressure, serum potassium and serum creatinine. RESULTS: No statistical difference was found for systolic blood pressure, diastolic blood pressure, or s...
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来源期刊
Journal of Managed Care Pharmacy
Journal of Managed Care Pharmacy 医学-卫生保健
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