VITAL研究后:补充维生素D是必要的吗?

R. Sakamoto
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引用次数: 0

摘要

收稿日期:2019年9月01日;录用日期:2019年9月16日;向公众宣传维生素D及其益处,特别是其对心血管和癌症等非骨骼慢性疾病的保护作用,仍然具有挑战性和令人困惑。最近的维生素D和Omega-3脂肪酸(VITAL)研究结果,一项随机临床试验(RCT) b[2]进一步使公众不信任维生素D补充剂。我听到病人和医生都说:“维生素D不起作用”,也许是因为他们把VITAL研究的负面结果等同于补充维生素D(胆钙化醇)根本没有效果。这种误解可能会导致科学社会长期以来证明维生素D作用背后的科学的倒退。因此,这篇评论的目的是讨论VITAL研究的弱点,这可以帮助医疗从业者,因此,他们所服务的人群补充维生素D。
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After VITAL study: Is Vitamin D supplementation necessary?
Received: September 01, 2019; Accepted: September 16, 2019; Published: September 20, 2019 Informing the public about Vitamin D, its benefits, particularly its protective effects against non-skeletal chronic illnesses such as that of cardiovascular and cancer effects remains challenging and confusing [1]. The recent Vitamin D and Omega-3 fatty acid (VITAL) study results, a Randomized Clinical Trial (RCT) [2] has further thrown the public in mistrusting vitamin D supplementation. I hear patients and practitioners alike stating: “vitamin D does not work” perhaps because they equate the negative findings of the VITAL study to mean that vitamin D (cholecalciferol) supplementation is not effective at all. Such misunderstanding could lead to stepping backwards from what the scientific society has long proven the science behind Vitamin D’s effects. Hence, the purpose of this commentary is to discuss weaknesses in the VITAL’s study that could assist healthcare practitioners’ hence, the population they serve on vitamin D supplementation.
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