腹腔镜胆囊切除术中常规术中胆道造影

L. Sebastiano, Massafra Roberto, M. Fabio
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Conclusions: Intraoperative cholangiography performed routinely represents an important tool in diagnosing unsuspected Common Bile Duct Stones (CBDS) during LC. This attitude has prevented further surgical treatment for all patients with asymptomatic biliary calculosis. *Correspondence to: Lacitignola Sebastiano, Contrada Sicarico 181/A, 70043 Monopoli , Italy, Tel: +39-330-840630; E-mail: lacitignola@libero.it Received: November 02, 2019; Accepted: November 24, 2019; Published: November 28, 2019 Introduction The asymptomatic stones of the common bile duct (CBD) represents, even today, a considerable challenge for the surgeon despite the progress made both in endoscopy and laparoscopy. Just over 10 years ago, 10% of patients with symptomatic calculosis and 15% of those with acute cholecystitis had stones in the common bile duct. With the laparoscopic procedure the patients had the advantage of a more immediate and faster approach to cholecystectomy with a consequent reduction of choledocholithiasis. Even when all procedures are feasible, there are some techniques preferred to others. If the patient had cholecystectomy it is unanimous opinion that the choledochal lithiasis must be treated endoscopically through endoscopic retrograde cholangiopancreatography (ERCP) with Endoscopic Sphincterotomy (ES) reserving surgery in case of failure (5-10%) [1]. If the gallbladder is “in situ” the treatment is controversial i.e. ERCP followed by laparoscopic cholecystectomy (LC). Another possibility is to perform the cholecystectomy and to remove the CBD stones through the laparoscopy or to abandon the stones with subsequent ERCP after LC. Many surgeons agree with these options in relation to their personal experience as well as the various protocols to be followed. Our personal tendency is to treat the CBDS in a single time using all the possible surgical strategies in our possession and this our attitude is also confirmed by the positive results obtained over the years. Materials and methods From January 1995 to December 2017 we were collected the data of 8918 patients undergoing LC for symptomatic lithiasis in three different Institutions. Routine Intraoperative Cholangiography (IOC) was successfully performed in 8806 patients (98.8%). In the remaining 112 patients (1.2%) the failure was due to the technical difficulties. The preoperative suspicion of CBDS was based on the patient’s clinical history, on the possible appearance of jaundice or pancreatitis considering the high blood values of bilirubin (> 1.0 mg/dl) , alkaline phosphate (>147 U/dl), amylase (>115 U/dl) or the ultrasound documentation of CBDS or his diameter greater than 7 mm. If none of these elements is present, we consider the IOC routine. The common bile stones were found in 1631 patients (18,5%) with a preoperative diagnosis of 1458 cases (89,3%) and 173 cases (10,6%) discovered during the LC due to perioperative cholangiography. The ERCP with ES was performed successfully in 1221 patients (83,7%) who had a preoperative diagnosis of CBDS. The remaining 237 patients (16,2%) added to those they had an intraoperative diagnosis of CBDS were treated surgically as shown in table 1. Operative cholangiography was attempted in all patients using a 4-Fr catheter and a choledochoscopy was performed using a 7-FR size fiberscope introduced through the cystic duct or choledochotomy to confirm the complete bile duct clearance. The patients had follow-up at 6-12-24 months and was not found a residual or recurrence stones. The postoperative complications reported two cases of bilioma after removal of the T-tube and these patients were treated with conservative therapy. 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If the patient had cholecystectomy it is unanimous opinion that the choledochal lithiasis must be treated endoscopically through endoscopic retrograde cholangiopancreatography (ERCP) with Endoscopic Sphincterotomy (ES) reserving surgery in case of failure (5-10%) [1]. If the gallbladder is “in situ” the treatment is controversial i.e. ERCP followed by laparoscopic cholecystectomy (LC). Another possibility is to perform the cholecystectomy and to remove the CBD stones through the laparoscopy or to abandon the stones with subsequent ERCP after LC. Many surgeons agree with these options in relation to their personal experience as well as the various protocols to be followed. Our personal tendency is to treat the CBDS in a single time using all the possible surgical strategies in our possession and this our attitude is also confirmed by the positive results obtained over the years. 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引用次数: 1

摘要

目的:本研究分析术中胆道造影(IOC)在三家不同机构22年手术活动中对所有患者的价值,作为对该问题持续的科学关注的结果,我们制定了一套标准进行分析和讨论。材料与方法:选取1995年1月至2017年12月在三家医院行腹腔镜胆囊切除术的患者为研究对象。对一组患者进行分析,所有病例均行IOC。结果:我们在超过10%的患者中发现了未被怀疑的胆总管结石(CBDS)阳性结果,这一发现改变了IOC后患者的手术管理。该手术中位时间为10分钟,没有由IOC引起的并发症。结论:术中常规胆道造影是LC中诊断未怀疑的总胆管结石(CBDS)的重要工具。这种态度阻碍了所有无症状胆道结石患者的进一步手术治疗。*通信:Lacitignola Sebastiano, Contrada Sicarico 181/A, 70043 Monopoli, Italy,电话:+39-330-840630;邮箱:lacitignola@libero.it收稿日期:2019年11月02日;录用日期:2019年11月24日;尽管在内窥镜和腹腔镜检查方面取得了进展,但即使在今天,胆总管(CBD)的无症状结石对外科医生来说仍然是一个相当大的挑战。就在10多年前,10%的症状性结石患者和15%的急性胆囊炎患者在胆总管有结石。采用腹腔镜手术,患者的优点是更直接、更快地进行胆囊切除术,从而减少胆总管结石。即使所有的程序都是可行的,也有一些技术优于其他技术。如果患者行胆囊切除术,一致认为胆总管结石必须在内镜下通过内镜逆行胆管造影(ERCP)和内镜下括约肌切开术(ES)保留手术治疗,以防手术失败(5-10%)。如果胆囊“原位”,治疗方法是有争议的,即ERCP之后是腹腔镜胆囊切除术(LC)。另一种可能性是行胆囊切除术,通过腹腔镜切除CBD结石,或在LC后用ERCP放弃结石。许多外科医生根据他们的个人经验和需要遵循的各种方案同意这些选择。我们的个人倾向是使用我们所拥有的所有可能的手术策略在一次治疗CBDS,我们的态度也被多年来取得的积极结果所证实。材料与方法1995年1月至2017年12月,我们收集了三家不同机构8918例接受LC治疗的症状性结石患者的资料。术中常规胆道造影(IOC)成功8806例(98.8%)。在其余112例(1.2%)患者中,失败是由于技术困难。术前对CBDS的怀疑是基于患者的临床病史,考虑到血中胆红素(> 1.0 mg/dl)、碱性磷酸盐(>147 U/dl)、淀粉酶(>115 U/dl)或CBDS的超声记录或其直径大于7 mm,考虑可能出现黄疸或胰腺炎。如果这些元素都不存在,我们就考虑IOC例程。常见胆结石1631例(18.5%),术前诊断1458例(89.3%),围术期胆道造影发现173例(10.6%)。术前诊断为CBDS的1221例患者(86.7%)成功行ERCP合并ES。其余237例(16.2%)患者加上术中诊断为CBDS的患者接受手术治疗,见表1。所有患者均使用4-Fr导管进行手术胆道造影,并使用7-FR尺寸的纤维镜通过胆囊管或胆道切开术进行胆道镜检查,以确认胆管完全清除。随访6-12-24个月,未发现结石残留或复发。术后并发症报告2例拔除t管后胆囊瘤,均予保守治疗。未发现死亡率。
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Routine intraoperative cholangiography during laparoscopic cholecystectomy
Objectives: The present study analyses the value of intraoperative cholangiography (IOC) performed in all patients during 22 years of surgical activity in three different Institutions and, as a result a continuous scientific concern on the matter, we developed a set of criteria that are analysed and discussed. Materials and methods: We studied the patients subjected to laparoscopic cholecystectomy in three hospitals between January 1995 and December 2017. A group of patients were analysed, IOC was performed in all cases. Results: we had a positive results of common bile duct stones (CBDS) unsuspected in more than 10%, a finding that changed surgical management of patient after IOC. This procedure required a median period of 10 minutes and there were no complications caused by IOC. Conclusions: Intraoperative cholangiography performed routinely represents an important tool in diagnosing unsuspected Common Bile Duct Stones (CBDS) during LC. This attitude has prevented further surgical treatment for all patients with asymptomatic biliary calculosis. *Correspondence to: Lacitignola Sebastiano, Contrada Sicarico 181/A, 70043 Monopoli , Italy, Tel: +39-330-840630; E-mail: lacitignola@libero.it Received: November 02, 2019; Accepted: November 24, 2019; Published: November 28, 2019 Introduction The asymptomatic stones of the common bile duct (CBD) represents, even today, a considerable challenge for the surgeon despite the progress made both in endoscopy and laparoscopy. Just over 10 years ago, 10% of patients with symptomatic calculosis and 15% of those with acute cholecystitis had stones in the common bile duct. With the laparoscopic procedure the patients had the advantage of a more immediate and faster approach to cholecystectomy with a consequent reduction of choledocholithiasis. Even when all procedures are feasible, there are some techniques preferred to others. If the patient had cholecystectomy it is unanimous opinion that the choledochal lithiasis must be treated endoscopically through endoscopic retrograde cholangiopancreatography (ERCP) with Endoscopic Sphincterotomy (ES) reserving surgery in case of failure (5-10%) [1]. If the gallbladder is “in situ” the treatment is controversial i.e. ERCP followed by laparoscopic cholecystectomy (LC). Another possibility is to perform the cholecystectomy and to remove the CBD stones through the laparoscopy or to abandon the stones with subsequent ERCP after LC. Many surgeons agree with these options in relation to their personal experience as well as the various protocols to be followed. Our personal tendency is to treat the CBDS in a single time using all the possible surgical strategies in our possession and this our attitude is also confirmed by the positive results obtained over the years. Materials and methods From January 1995 to December 2017 we were collected the data of 8918 patients undergoing LC for symptomatic lithiasis in three different Institutions. Routine Intraoperative Cholangiography (IOC) was successfully performed in 8806 patients (98.8%). In the remaining 112 patients (1.2%) the failure was due to the technical difficulties. The preoperative suspicion of CBDS was based on the patient’s clinical history, on the possible appearance of jaundice or pancreatitis considering the high blood values of bilirubin (> 1.0 mg/dl) , alkaline phosphate (>147 U/dl), amylase (>115 U/dl) or the ultrasound documentation of CBDS or his diameter greater than 7 mm. If none of these elements is present, we consider the IOC routine. The common bile stones were found in 1631 patients (18,5%) with a preoperative diagnosis of 1458 cases (89,3%) and 173 cases (10,6%) discovered during the LC due to perioperative cholangiography. The ERCP with ES was performed successfully in 1221 patients (83,7%) who had a preoperative diagnosis of CBDS. The remaining 237 patients (16,2%) added to those they had an intraoperative diagnosis of CBDS were treated surgically as shown in table 1. Operative cholangiography was attempted in all patients using a 4-Fr catheter and a choledochoscopy was performed using a 7-FR size fiberscope introduced through the cystic duct or choledochotomy to confirm the complete bile duct clearance. The patients had follow-up at 6-12-24 months and was not found a residual or recurrence stones. The postoperative complications reported two cases of bilioma after removal of the T-tube and these patients were treated with conservative therapy. No mortality was found.
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