疼痛结局与种族和阿片类药物治疗的关系:退伍军人的回顾性队列研究。

Diana J. Burgess, A. Gravely, D. Nelson, M. Bair, R. Kerns, D. Higgins, M. Farmer, M. Partin
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引用次数: 9

摘要

我们研究了疼痛结局(疼痛干扰、感知疼痛治疗效果)是否因种族而异,以及阿片类药物的使用是否会调节这些关联。这些分析是一项回顾性队列研究的一部分,研究对象是3505名黑人和46203名非西班牙裔、白人退伍军人事务部(VA)的慢性肌肉骨骼疼痛患者,这些患者响应了2007年VA患者医疗保健经历调查(SHEP)。我们使用电子病历数据来识别诊断后(疼痛诊断索引访问)和SHEP索引访问(使一个人有资格完成SHEP的访问)之前一年的药物疼痛治疗处方;疼痛结果来自于SHEP。我们发现种族与疼痛干扰或疼痛治疗的感知有效性之间没有显著的关联。在疼痛诊断指数访问和SHEP指数访问之间服用阿片类药物的VA患者报告的疼痛对SHEP的干扰大于未服用阿片类药物的患者。阿片类药物处方与大多数患者感知的治疗效果无关。研究结果提出了关于阿片类药物对肌肉骨骼疼痛的益处的问题,并指出需要替代治疗来解决慢性非癌性疼痛。
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Association between pain outcomes and race and opioid treatment: Retrospective cohort study of Veterans.
We examined whether pain outcomes (pain interference, perceived pain treatment effectiveness) vary by race and then whether opioid use moderates these associations. These analyses are part of a retrospective cohort study among 3,505 black and 46,203 non-Hispanic, white Department of Veterans Affairs (VA) patients with diagnoses of chronic musculoskeletal pain who responded to the 2007 VA Survey of Healthcare Experiences of Patients (SHEP). We used electronic medical record data to identify prescriptions for pharmacologic pain treatments in the year after diagnosis (Pain Diagnosis index visit) and before the SHEP index visit (the visit that made one eligible to complete the SHEP); pain outcomes came from the SHEP. We found no significant associations between race and pain interference or perceived effectiveness of pain treatment. VA patients with opioid prescriptions between the Pain Diagnosis index visit and the SHEP index visit reported greater pain interference on the SHEP than those without opioid prescriptions during that period. Opioid prescriptions were not associated with perceived treatment effectiveness for most patients. Findings raise questions about benefits of opioids for musculoskeletal pain and point to the need for alternative treatments for addressing chronic noncancer pain.
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