Sucralfate预防开放性胫骨骨折外固定器针点感染。

Androniki Drakou, Spyridon Sioutis, Ioannis Zafeiris, Fotini Soucacos, Vasileios Karampikas, Aikaterini Tsatsaragkou, Andreas F Mavrogenis, Dimitrios Koulalis
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引用次数: 0

摘要

钉部位感染是外固定器的主要并发症。最常见的病原体是表皮葡萄球菌和金黄色葡萄球菌。针孔感染的发生率在2%到30%之间。到目前为止,还没有令人满意的预防战略。因此,我们进行了这项研究,以评估在外伤性胫骨开放性骨折患者的外固定系统销钉周围应用25%三氯福凝胶的效果。我们前瞻性研究了两组使用外固定器治疗胫骨开放性骨折的患者。在A组患者中,使用生理盐水和普通敷料进行针刺部位护理,每天一次。在B组患者中,使用25%的硫糖铝凝胶进行针点护理。A组患者针部位感染的发生率为33.33%,B组为16.67%。与A组患者相比,B组患者的针部位感染率显著降低(p值=0.032)。没有患者出现与局部用药有关的任何并发症。硫糖酸盐可显著预防开放性胫骨骨折外固定器钉端感染。因此,它可以作为外固定器患者针点感染的预防性抗菌剂。
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Sucralfate Prevents Pin Site Infections of External Fixators in Open Tibia Fractures.

Pin site infections are the main complication of external fixators. The most common pathogens are Staphylococcus epidermidis and Staphylococcus aureus. The incidence of pin site infections ranges from 2% to 30%. Until now, no satisfactory prevention strategy exists. Therefore, we performed this study to assess the effect of a sucralfate gel 25% applied around the pins of external fixation systems in trauma patients with open tibia fractures. We prospectively studied two groups of patients with open tibia fractures treated with external fixators. In group A patients, pin site care was performed with the use of normal saline and plain dressings once a day. In group B patients, pin site care was performed with the use of sucralfate gel 25%. The incidence of pin site infections was 33.33% for patients of group A and 16.67% for patients of group B. Patients of group B showed significantly lower rate of pin site infections compared to patients of group A (p-value = 0.032). No patient experienced any complications related to the local application of the drug. Sucralfate significantly prevents pin site infections of external fixators in open tibia fractures. Therefore, it can be used as a preventive antimicrobial agent for pin site infections in patients with external fixators.

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来源期刊
CiteScore
1.20
自引率
0.00%
发文量
46
期刊介绍: MEDICAL IMPLANTS are being used in every organ of the human body. Ideally, medical implants must have biomechanical properties comparable to those of autogenous tissues without any adverse effects. In each anatomic site, studies of the long-term effects of medical implants must be undertaken to determine accurately the safety and performance of the implants. Today, implant surgery has become an interdisciplinary undertaking involving a number of skilled and gifted specialists. For example, successful cochlear implants will involve audiologists, audiological physicians, speech and language therapists, otolaryngologists, nurses, neuro-otologists, teachers of the deaf, hearing therapists, cochlear implant manufacturers, and others involved with hearing-impaired and deaf individuals.
期刊最新文献
The Need for Persistence in the Diagnosis of Mycobacterium Tuberculosis Mono-arthritis: A Unique Case Presentation. Association between Gingival Biotype and Crestal Bone Loss in Implants Placed in Anterior Maxilla. Ipsilateral Hip and Knee Reconstruction Using an Intramedullary Total Femoral Replacement System. Ultrasound-Guided Peripheral Nerve Blocks for Hip Surgery: A Concise Perspective. Sucralfate Prevents Pin Site Infections of External Fixators in Open Tibia Fractures.
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