在季节性病原体循环模式改变的条件下,优化炎症性和传染性呼吸道疾病的治疗

A. Gorelov, O. Kalyuzhin, S. Ryazantsev, M. Savenkova, E. Melekhina, A. V. Gurov
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引用次数: 0

摘要

每年,急性和慢性呼吸道传染病在世界和俄罗斯联邦的发病率和造成的损害程度方面都保持领先地位。呼吸道感染问题与儿童最为相关,因为这些疾病的发病率很高,并发症和慢性形式发展的风险增加。在COVID-19大流行的最后六个月及其结束后,人们注意到呼吸道病原体传播的某些特点,这使治疗策略的选择复杂化。急性呼吸道疾病的高多变性,存在不明和研究不足的病原体,混合呼吸道感染的频繁发生减少了有效使用致病因治疗的可能性。在这些情况下,激活人体自身先天和适应性免疫机制来对抗感染的手段发挥了重要作用,例如细菌裂解药物。目的:基于每周监测和流行病学研究,总结呼吸道病原体传播现状特征的相关数据,开发各种急慢性炎症性和传染性呼吸道疾病患者的治疗算法。关键词:急性呼吸道感染,COVID-19大流行,2022-2023流行季节,喉咙痛,慢性扁桃体炎,腺样体炎,治疗方法,细菌解菌药物
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Optimizing the treatment of inflammatory and infectious respiratory diseasesin conditions of changes in the circulation patterns of seasonal pathogens
Every year, acute and chronic infectious diseases of the respiratory tract maintain their leading positions in terms of incidence and the magnitude of the damage caused both in the world and in the Russian Federation. The problem of respiratory infections is most relevant in children due to high prevalence of these diseases and increased risk of complications and development of chronic forms. In the last six months of the COVID-19 pandemic and after its completion, сertain peculiarities of circulation of respiratory pathogens have been noted, which complicate the choice of treatment tactics. The high polyetiologicity of acute respiratory diseases, the existence of unidentified and poorly studied pathogens, the frequent occurrence of mixed respiratory tract infections reduce the possibilities for the effective use of etiotropic therapy. In these conditions, an important role is assigned to means that activate the body's own innate and adaptive immune mechanisms to fight infection, such as bacterial lysate medicines. Objective: Generalization of relevant data on the current features of circulation of respiratory pathogens based on weekly monitoring and epidemiological studies and the development of algorithms for the treatment of patient with various acute and chronic inflammatory and infectious respiratory diseases. Key words: acute respiratory infections, COVID-19 pandemic, 2022–2023 epidemic season, sore throat, chronic tonsillitis, adenoiditis, treatment algorithms, bacterial lysate medicines
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来源期刊
Voprosy Prakticheskoi Pediatrii
Voprosy Prakticheskoi Pediatrii Medicine-Pediatrics, Perinatology and Child Health
CiteScore
1.20
自引率
0.00%
发文量
50
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