{"title":"伏立康唑和华法林在肾移植患者体内可能的相互作用","authors":"A. Mathis, D. Schiller","doi":"10.2174/1874418400802010029","DOIUrl":null,"url":null,"abstract":"A potential warfarin - voriconazole interaction has been identified in one study involving healthy individuals. We report a case where addition of voriconazole possibly increased the international normalized ratio (INR) in a renal transplant patient taking warfarin. The INR elevation was resistant to reversal agents, and the situation may have ulti- mately contributed to a thrombotic episode.","PeriodicalId":90368,"journal":{"name":"The open transplantation journal","volume":"2 1","pages":"29-34"},"PeriodicalIF":0.0000,"publicationDate":"2008-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Possible Interaction of Voriconazole and Warfarin in a Renal Transplant Recipient\",\"authors\":\"A. Mathis, D. Schiller\",\"doi\":\"10.2174/1874418400802010029\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A potential warfarin - voriconazole interaction has been identified in one study involving healthy individuals. We report a case where addition of voriconazole possibly increased the international normalized ratio (INR) in a renal transplant patient taking warfarin. The INR elevation was resistant to reversal agents, and the situation may have ulti- mately contributed to a thrombotic episode.\",\"PeriodicalId\":90368,\"journal\":{\"name\":\"The open transplantation journal\",\"volume\":\"2 1\",\"pages\":\"29-34\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2008-08-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The open transplantation journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1874418400802010029\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The open transplantation journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874418400802010029","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A Possible Interaction of Voriconazole and Warfarin in a Renal Transplant Recipient
A potential warfarin - voriconazole interaction has been identified in one study involving healthy individuals. We report a case where addition of voriconazole possibly increased the international normalized ratio (INR) in a renal transplant patient taking warfarin. The INR elevation was resistant to reversal agents, and the situation may have ulti- mately contributed to a thrombotic episode.
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