高脂血症Wistar大鼠降血脂及降低TNF-α作用的研究

R. Nath
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引用次数: 1

摘要

方法:将30只雄性成年wistar大鼠分为5组(n=6),分别饲喂高脂饲料(HFD)诱导高脂血症6周。诱导期结束后,ii ~ iv组大鼠分别给予100、200、400 mg/kg体重的榕叶灌胃,V组给予40 mg/kg体重的阿托伐他汀灌胃4周。测定血浆肿瘤坏死因子-α和血脂水平进行评价。
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Evaluation of Hypolipidemic and TNF-α Lowering Effect of Ficus Religiosa in Dyslipidemic Wistar Rats
Methods: 30 male adult wistar rats were divided into 5 groups (n=6) and were fed with high fat diet (HFD) for 6 weeks to induce hyperlipidemia. After the induction period, rats in groups II-IV were treated with Ficus religiosa 100, 200, and 400 mg/kg body weight respectively and group V with atorvastatin 40 mg/kg body weight orally for 4 weeks. Plasma Tumor necrosis factor-α and plasma lipid profile levels were measured for evaluation.
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