欧洲成年人注意缺陷/多动障碍的诊断、治疗和疾病负担

IF 2.3 Q2 MEDICINE, GENERAL & INTERNAL Pragmatic and Observational Research Pub Date : 2014-07-28 DOI:10.2147/POR.S64348
S. Able, V. Haynes, Jihyung Hong
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引用次数: 11

摘要

目的定量分析欧洲(德国、英国、瑞典、丹麦和荷兰)的注意力缺陷/多动障碍(ADHD)负担,描述导致ADHD诊断和治疗的成人经验,并将这些发现与美国的结果进行比较。调查对象和方法数据收集自一项针对欧洲和美国成年人的基于网络的国际调查。社会人口统计学、合并症、工作效率/活动障碍和医疗保健利用报告ADHD诊断的成年人(n=431)和相似数量的无ADHD成年人(n=449)进行了比较。被调查者对ADHD的诊断和治疗经历以及对心理社会功能的感知影响进行了评估。此外,还进行了多变量回归分析,比较了两个地区ADHD负担的差异。结果这两个地区患有ADHD的成年人结婚、就业、健康评价为“好”/“非常好”/“优秀”的可能性普遍较低,吸烟、酗酒、有其他精神健康问题、工作效率/活动障碍和使用医疗资源的可能性较高。尽管在诊断前咨询的医疗保健专业人员的专业在两个地区之间是相似的,但在接受首次ADHD诊断所需的时间长度上存在显著差异。只有55%的欧洲受访者在首次咨询医生后的6个月内就ADHD症状得到了诊断,而在美国,这一比例为90%。回归分析的结果证实了ADHD对社会心理功能、工作效率的损害以及在欧洲就诊的总人数有更大的影响。结论:研究结果显示,ADHD对成年人的一系列结果有显著影响,包括社会、家庭和工作关系,与健康相关的工作效率损害,以及医疗保健资源的使用,欧洲研究参与者的疾病负担普遍高于美国。
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Diagnosis, treatment, and burden of illness among adults with attention-deficit/hyperactivity disorder in Europe
Purpose To quantitatively address the burden of attention-deficit/hyperactivity disorder (ADHD) in Europe (Germany, the UK, Sweden, Denmark, and the Netherlands), to describe adult experience leading to diagnosis and treatment of ADHD, and to compare those findings with results from the US. Survey respondents and methods Data were collected from an international web-based survey of adults from Europe and the US. Sociodemographics, comorbidities, work productivity/activity impairments, and health care utilization of adults reporting an ADHD diagnosis (n=431) and a similar number of adults without ADHD (n=449) were compared. Respondents’ experiences with the diagnosis and treatment of ADHD and the perceived effects of the condition on psychosocial functioning were assessed. In addition, multivariate regression analyses were performed to compare the burden of ADHD between the two regions. Results Adults with ADHD in both regions were generally less likely to be married, employed, or rate their health as good/very good/excellent and were more likely to smoke, have experienced alcoholism, have other mental health conditions, have work productivity/activity impairments, and use health care resources. Although the specialties of health care professionals consulted prior to diagnosis were similar between the two regions, there was a notable difference in the length of time it took to receive a first ADHD diagnosis. Only 55% of European respondents received a diagnosis within 6 months of their first physician consultation regarding their ADHD symptoms, compared to 90% in the US. The results of regression analyses confirmed a greater impact of ADHD on psychosocial functioning, work productivity impairments, and the total number of provider visits in Europe. Conclusion The results revealed a significant impact of ADHD on adults over a range of outcomes, including social, family, and work relationships, health-related work productivity impairment, and health care resource use, with a generally greater burden of illness among European study participants than those from the US.
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Pragmatic and Observational Research
Pragmatic and Observational Research MEDICINE, GENERAL & INTERNAL-
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期刊介绍: Pragmatic and Observational Research is an international, peer-reviewed, open-access journal that publishes data from studies designed to closely reflect medical interventions in real-world clinical practice, providing insights beyond classical randomized controlled trials (RCTs). While RCTs maximize internal validity for cause-and-effect relationships, they often represent only specific patient groups. This journal aims to complement such studies by providing data that better mirrors real-world patients and the usage of medicines, thus informing guidelines and enhancing the applicability of research findings across diverse patient populations encountered in everyday clinical practice.
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